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Insect Cell Cultures: Fundamentals and Applied Aspects

Series: Current Applications of Cell Culture Engineering Volume: 2

Edited By: JM Vlak, CD De Gooijer, J Tramper and HG Miltenburger

Kluwer Academic Publishers

Hardback | Dec 1995 | #61537 | ISBN: 0792334035
Availability: Usually dispatched within 1-2 weeks Details
NHBS Price: £272.00 $333/€305 approx

About this book

Insect Cell Cultures: Fundamental and Applied Aspects is a comprehensive reference work, covering the key issues involved in nearly 30 review papers: cell lines (development, characterisation, physiology, cultivation and medium design); viruses (virus-cell interactions, replication, recombinant construction, infection kinetics, post-translational modification and passage effects); engineering (shear, bioreactors including perfusion, immobilisation, scale-up and modelling, downstream processing); applications; economics and regulatory aspects. This book is intended for cell biologists, biochemists, molecular biologists, virologists, immunologists and other basic and applied disciplines related to cell culture engineering, both academic and industrial.

'In summary, this book covers a wide range of aspects relating to insect cell culture and the baculovirus expression system. It is an authoritative volume which is clearly and conci8sely written by experts selected from industry and academia and is to be highly recommended.' Entomologia Experimentalis et Applicata, 87 (1998) 'This is an authoritative reference text written by leading experts in their respective fields of insects cell culture. The book targets a potential audience ranging from students and researchers in academia through to those concerned in industry with biotechnology applications.' SGM Quarterly, August (1997)


Part 1 Insect cell lines: development and characterization of insect cell lines, D. Lynn and J.L. Vaughn; insect tissue culture, D. Baines; transgenic insect cells, A. Fallon; insect cell physiology, M.M. Ataai; insect cell cultivation - growth and kinetics, G. Schmid; medium design for insect cell culture, E.-J. Schlaeger. Part 2 Viruses: baculovirus - insect interactions, G.S. Blissard; baculovirus replication in cultured insect cells, P. Faulkner; construction of baculovirus recombinants, P.A. Kitts; infection kinetics of baculoviruses in insect cells, D. Hammer. passage effect of virus infection in insect cells, P.J. Krell; post-translational modification in insect cells, H.-D. Klenk; productivity of insect cells for recombinant proteins, J.E. Maruniak. Part 3 Engineering aspects: shear sensitivity of insect cells, J. Chalmers; insect cell bioreactors, S.N. Agathos; perfusion reactors in recombinant protein production in insect cells, V. Jager; immobilization of insect cells, M.F.A. Goosen; modelling of insect cell physiology, J. Power and L.K. Nielsen; scale up of insect cell cultures, J. Tramper; down-stream processing of insect cell cultures, A. Bernard. Part 4 Applications: "in vitro" production of wild type and recombinant baculoviruses, S.A. Weiss and S. Reid; parvovirus diagnostics and vaccine production in insect cells, J.I. Casal; HIV diagnostics and vaccine production in insect cells, G.E. Smith; hog cholera virus vaccine from insect cells, R. Moorman; production of multidomain complement glycoproteins in insect cells, P. Zavodski and S. Cseh. Part 5 Economic and regulatory aspects: economics of baculovirus - insect cell production systems, D.J. Rhodes; biosafety and containment of insect cells, G. Stacey; Regulatory issues in the use of insect cell culture, F.L.J. van Lier.

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