Cellular and Molecular Basis of Regeneration From Invertebrates to Humans

About this book

Provides an extensive overview of the fundamental issues that underlie regeneration and discusses selected models from invertebrates to mammals. It also examines the issue of regeneration from an evolutionary perspective in order to address the issue of why regenerative ability has decreased through evolution and assess how far we are from increasing the regenerative potential in mammals.

Contents

Regenerative through phylogenesis; development and regeneration, with special emphasis on the amphibian limb; progenitor cells - origin by the reversal of the dedifferentiated state; the role of the nervous system in regeneration; hydra; planarians; the dermal skeleton; the tetrapod limb; trandifferentian as a basis of eye lens regeneration; the sensory epithelia of the ear and lateral line; the spinal cord; skin repair in the embryo and adult; the bone; the muscle; the heart; the axon; brain and spinal cord; bridging the gap - restoration of structure and function in humans.

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