Books  Animal & General Biology  Biochemistry & Molecular Biology 

Virus Dynamics: Mathematical Principles of Immunology and Virology

By: Martin Nowak and Robert May

237 pages, Figs, tabs

Oxford University Press

Paperback | Nov 2000 | #90324 | ISBN: 0198504179
Availability: Usually dispatched within 2-3 weeks Details
NHBS Price: £72.50 $92/€86 approx
Hardback | Dec 1999 | #90323 | ISBN: 0198504187
Out of Print Details

About this book

Describes the emerging field of theoretical immunology, in particular the use of mathematical models to describe the spread of infectious diseases within patients.
'... an excellent introduction to a field that has the potential to advance substantially our understanding of the complex interplay between virus and host' Nature

... an excellent introduction to a field that has the potential to advance substantially our understanding of the complex interplay between virus and host Nature


Contents

Preface; 1. Introduction: Viruses, immunity, equations; 2. HIV; 3. The basic model of virus dynamics; 4. Anti-viral drug therapy; 5. Dynamics of hepatitis B virus; 6. Dynamics of immune responses; 7. How fast do immune responses eliminate infected cells?; 8. What is a quasispecies; 9. The frequency of resistant mutant virus before anti-viral therapy; 10. Emergence of drug resistance; 11. Timing the emergence of resistance; 12. Simple antigenic variation; 13. Advanced antigenic variation; 14. Multiple epitopes; 15. Everything we know so far and beyond; Appendix A - Dynamics of resistance in different types of infected cells; Appendix B - Analysis of multiple epitope dynamics

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