Virus Dynamics Mathematical Principles of Immunology and Virology

About this book

Describes the emerging field of theoretical immunology, in particular the use of mathematical models to describe the spread of infectious diseases within patients.
'... an excellent introduction to a field that has the potential to advance substantially our understanding of the complex interplay between virus and host' Nature

Contents

Preface; 1. Introduction: Viruses, immunity, equations; 2. HIV; 3. The basic model of virus dynamics; 4. Anti-viral drug therapy; 5. Dynamics of hepatitis B virus; 6. Dynamics of immune responses; 7. How fast do immune responses eliminate infected cells?; 8. What is a quasispecies; 9. The frequency of resistant mutant virus before anti-viral therapy; 10. Emergence of drug resistance; 11. Timing the emergence of resistance; 12. Simple antigenic variation; 13. Advanced antigenic variation; 14. Multiple epitopes; 15. Everything we know so far and beyond; Appendix A - Dynamics of resistance in different types of infected cells; Appendix B - Analysis of multiple epitope dynamics

Customer Reviews