Books  Animal & General Biology  Biochemistry & Molecular Biology 

Signaling and the Cytoskeleton

By: KL Carraway and CAC Carraway


Hardback | Dec 1998 | #95737 | ISBN: 3540642153
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NHBS Price: £103.00 $126/€116 approx

About this book

This monograph explores the relationships between cell signalling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between the two very active aspects of molecular cell biology. It covers the two main - and reciprocal - questions of these relationships: how is the structure and function of the cytoskeleton affected by external signals which impinge on the cell?; how does the cytoskeleton influence the cellular signalling processes which determine cell behaviour?


Local regulation of allograft rejection; pharmacokinetic advantage of regional drug therapy; pump-based local infusion in rat allograft models; pump-based local infusion in canine allograft models; intrarenal heparin, 6-mercaptopurine, prednisolone and mizoribine; intraportal cyclosporine A; other drug targetting systems for achieving local immunosuppression; liposomal cyclosporine A; topical cyclosporine A in skin allografting; gene transfer to the transplanted organ; cellular cotransplantation/genetic engineering/immune privileged site.

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