This book addresses the regulation of the eukaryotic cell cycle. The progress in understanding the modus operandi of the cell cycle machinery and its central role in controlling cell proliferation has awakened a great deal of interest. The aim of this book is to make the background of the cell cycle field as unambiguous and clear as possible by delineating what is commonly accepted in the field from the unsolved problems. It is thus intended to serve a large audience: basic and clinical scientists involved in the study of cell growth, differentiation, senescence, apoptosis, and cancer as well as graduate and postgraduate students.
Regulation of the G1 Phase; Regulation of S-Phase; Regulation of the G2 to M Transition; Cdk Regulation by Phosphorylation; Regulation of the Cell Cycle by Cdk Inhibitors; Regulation of Cyclin-Dependent Kinases by the Ubiquitin Pathway; Regulation of the Cell Cycle by the Rb Tumor Suppressor Family; Control of Proliferation by myc; Growth Regulation by the E2F Transcription Factor Family;
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