Books  Animal & General Biology  Biochemistry & Molecular Biology 

Protein Structure Prediction

Handbook / Manual

Series: Methods in Molecular Biology

By: D Webster

Humana Press

Hardback | Dec 1999 | #104086 | ISBN: 0896036375
Availability: Usually dispatched within 1-2 weeks Details
NHBS Price: £72.50 $89/€81 approx

About this book

Covers many aspects, from sequence analysis, which is often the starting point for algorithms, through secondary and tertiary methods, to the prediction of docked complexes, which are essential to fully understand biological function.

The organization of this book is excellent. Eighteen chapters lead the reader through the entire process. Many of the authors are, in fact, the developers of some commonly used methods and offer a first-hand introduction to their software. The emphasis is on providing a practical handbook most chapters contain detailed tutorials and worked-through examples that give a real-life flavor to the explanations. - Journal of American Chemical Society The book is a collection of 18 review articles, many written by distinguished experts in their field, providing an overview of the major aspects of protein structure prediction. About half of the articles deal with specific software packages, many of which are free to academic users, where the author of the software discussed. a useful reference to address for anyone thinking of dipping their toes into this exciting field. - Biochemistry and Molecular Biology Education


An Overview of Protein Structure Prediction; Multiple Sequence Alignment; Protein Structure Comparison; Discovering Patterns Conserved in Sets of Unaligned Protein Sequences; Identification of Domains From Protein Sequences; Prediction of Secondary Structure; Comparative Protein Structure Modeling: Introduction and Practical Examples with MODELLER; A Practical Guide to Protein Structure Prediction; Derivation and testing Residue-Residue Mean-Force Potentials for Use in Protein Structure Prediction; Genetic Algorithms and Protein Folding; Scoring Functions for Ab-initio Methods; Ab Initio Loop Modeling and Its Application to Homology Modeling; The Dead-End Elimination Theorem: Mathematical Aspects, Implementation, Optimisations, Evaluation and Performance; Classification of Protein Folds; Modeling Transmembrane Helix Bundles by Restrained MD Simulations; Predictive Models of Protein Active Sites; Flexible Docking of Peptide Ligands to Proteins; Geometrical Docking Algorithms: A Practical Approach; Protein-Protein Docking: Generation and Filtering of Complexes

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