Books  Animal & General Biology  Biochemistry & Molecular Biology 

Apoptosis: Mechanisms and Role in Disease

Series: Results and Problems in Cell Differentiation Volume: 24

Edited By: S Kumar

254 pages, 22 figs


Hardback | Dec 1998 | #104138 | ISBN: 3540646248
Availability: Usually dispatched within 1-2 weeks Details
NHBS Price: £115.50 $141/€130 approx

About this book

This volume deals with many of the recent advances made in uncovering the molecular and cellular basis of apoptosis and elaborates on how this accumulating knowledge is helping us to understand the significance of apoptosis in pathogenesis of diseases arising from inappropriate cell death. Further, mechanistic aspects of cell death and role of apoptosis in disease is covered.


Caspases in Cell Death * Proteolytic Targets in Cell Death * The Point of No Return: Mitochondria, Caspases, and the Commitment to Cell Death * Serpins and Regulation of Cell Death * The IAP Family of Apoptotic Regulators * Apoptosis Versus Necrosis: The Shape of Neuronal Cell Death * Prevention of Neuronal Cell Death by Bcl-2 * CD95 (APO-1/Fas) in Hematopoietic Diseases * The Cornified Envelope: A Model of Cell Death in the Skin * Radiation-Induced Cell Death and its Implications in Human Disease * Influence of Programmed Cell Death on T Cell Homeostasis.

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