Part I. Genes, Molecules and Tooth Initiation: 1. Homeobox genes in initiation and shape of teeth during development in mammalian embryos Paul T. Sharpe; 2. Return of lost structure in the developmental control of tooth shape Jukka Jernvall and Irma Thesleff; 3. Molecules implicated in odontoblast terminal differentiation and dentinogenesis J. V. Ruch and H. Lesot; 4. Enamel biomineralization: the assembly and disassembly of the protein extracellular organic matrix Alan G. Fincham, Janet Moradian-Oldak, Michael L. Paine, Malcolm L. Snead and Margarita Zeichner-David; Part II. Tooth Tissues: Development and Evolution: 5. Evolutionary origins of dentine in the fossil record of early vertebrates: diversity, development and function Moya Smith and Ivan Sansom; 6. Pulpo-dentinal interactions in development and repair of dentine Tony Smith; 7. Prismless enamel in amniotes: terminology, function and evolution P. Martin Sander; 8. Two different strategies in enamel differentiatioerentiation: marsupialia versus eutheria W. von Koenigswald; 9. Incremental markings in enamel and dentine: what they can tell us about the way teeth grow M. C. Dean; Part III. Evolution of Tooth Shape and Dentition: 10. Evolutionary origins of teeth and jaws: developmental models and phylogenetic patterns M. M. Smith and M. I. Coates; 11. Development and evolution of dentition patterns and their genetic basis Z. Zhao, K. M. Weiss and D. W. Stock; 12. Evolution of tooth attachment in lower vertebrates to tetrapods P. Gaengler; 13. Tooth replacement patterns in non-mammalian vertebrates B. K. Berkovitz; 14. The evolution of tooth shape and tooth function in primates P. M. Butler; 15. 'Schultz's Rule' and the evolution of tooth emergence and replacement patterns in primates and ungulates B. H. Smith; Part IV. Macrostructure and Function: 16. Developmental plasticity in the dentition of a heterodont polyphyodont fish species A. Huysseune; 17. Enamel microporosity and its functional implications R. P. Shellis and G. H. Dibdin; 18. Pathways to functional differentiation in mammalian enamel J. M. Rensberger; 19. Trends in the evolution of molar crown types in ungulate mammals: evidence from the northern hemisphere J. Jernvall, J. P. Hunter and M. Fortelius; 20. Function of postcanine tooth crown shape in mammals P. W. Lucas and C. R. Peters; 21. Primate dental functional morphology revisited M. F. Teaford; Index.