Today, there is considerable literature regarding the subject of antimicrobial resistance. However most of this information is based on information from developed countries. Very little organized information is available about the subject that critically examines the problem in developing countries. Scattered literature is available in various forms in journals that are often not easily accessible to the affected developing countries.
The objective of the book is to put together data and information about the problem of antimicrobial resistance in developing countries addressing the general global perspectives, the risk factors, the current rates, trends, and possibilities for containment as they relate to specific conditions in those developing countries.
Section I: General Issues in Antimicrobial Resistance. Global perspectives of the Resistance Problem.- Mechanisms of Resistance.- Poverty and Root Causes of Resistance in Developing Countries.- What the Future Holds for Resistance in Developing Countries.- The Introduction of Antimicrobial Agents in Poor-resource Countries: Impact on the Emergence of Resistance.- Section II: The Human Impact of Resistance. HIV Resistance in Developing Countries.- Drug Resistance in Malaria in Developing Countries.- Drug Resistance in Tuberculosis in Developing Countries.- Antifungal Drug Resistance in Developing Countries.- Antimicrobial Resistance in African Trypanosomiasis.- Resistance in Enteric Pathogens in Developing Countries.-Bacterial Resistant Infections in Resource-Limited Countries.- Prevalence of Resistant Enterococci in Developing Countries.- Antimicrobial Resistance in Gram-negative Bacteria from Developing Countries.- Resistance in Reservoirs and Human Commensals.- Section III: Antimicrobial Use and Misuse. Determinants of Antimicrobial Use: Poorly Understood - Poorly Researched.- Antimicrobial Use and Antimicrobial Resistance in African Countries.- Antimicrobial Use and Antimicrobial Resistance in Asian Countries.- Antimicrobial Use and Antimicrobial Resistance in Latin America and the Caribbean Countries.- Hospital Infections by Antimicrobial Resistant Organisms in Developing Countries.- Section IV: Cost, Policy and Regulation of Antimicrobials. Economic Burden of Antimicrobial Resistance.- Health Systems Strengthening to Improve Access to Antimicrobials and the Containment of Resistance.- The Role of Unregulated Sale and Dispensing of Antimicrobial Agents on the Development of Antimicrobial Resistance in Developing Countries.- Counterfeit and Substandard Anti-Infectives in Developing Countries.- Section V: Strategies to contain AMR. Containment of Antimicrobial Resistance in Developing Countries & Lessons Learned.- Surveillance of Antimicrobial Resistance.- Vaccines: A Cost-effective Strategy to Contain Antimicrobial Resistance.- Teaching Antibiotic Prescription Practices in Medical Schools in Developing Countries.- Containing Global Antibiotic Resistance: Ethical Drug Promotion in the Developing World.- News Media Reporting of Antimicrobial Resistance in Latin America and India.
"[...] In dem Buch werden von insgesamt 30 Autorinnen (Mikrobiologen und Infektiologen) in hervorragenden Ubersichtsartikeln all die genannten Probleme dargestellt. Die Literaturangaben sind auf dem neuesten Stand. Fur alle die sich mit Infektionserkrankungen hier und in armen Landern beschaftigen ist das Buch ein Muss und kann uneingeschrankt empfohlen werden."
- Dr Gerhard Schwarzkopf-Steinhauser, in: Pharma-Brief, May/June/2010, Issue 4-5, S. 4 f.