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Applied Molecular Genetics of Fungi

Series: British Mycological Society Symposia Volume: 18

Edited By: JF Perberdy, CE Caten, JE Ogden and JW Bennett

Cambridge University Press

Hardback | Oct 1991 | #30715 | ISBN: 0521415713
Availability: Usually dispatched within 5 days Details
NHBS Price: £66.99 $93/€76 approx

About this book

The interactions of fungi with mankind are both beneficial and harmful and are deeply rooted in the history of human society and agriculture. Over the centuries humans have sought to manipulate the growth of fungi to their advantage; the methods used, though largely empirical, have often been highly successful. Since the initial development of recombinant DNA technology in bacteria in the early 1970s, biology has been undergoing a molecular revolution which is spreading to all organisms, including fungi. The approach and techniques of molecular biology enable us to ask and answer fundamental questions about many aspects of fungal biology, and open the way to the directed manipulation of fungal metabolism. This book highlights the rapid development of gene transfer and cloning techniques in fungi and the ways in which these are being exploited in species of economic importance either in biotechnology or as plant pathogens.

an excellent contribution to the British Mycological Society symposium series...focuses on recent developments in methods for gene manipulation in fungi together with specific examples of how these techniques are being used to exploit industrially important species for use in heterologous gene expression and strain improvement and for the analysis of plant fungal pathogenesis...the editors and authors of this volume have produced an excellent reference source for biotechnologists in industrial mycology as well as for institutional libraries serving students of fungal molecular biology. Kerry O'Donnell, Mycologia " excellent review of all the rapid developments made in these fields in the last decade." MCS-SMC Bulletin "It may sound like an oxymoron, but gene transfer technology still has its major applications in basic research. For example, it can be used to identify pathogenicity genes in phytopathogenic fungi (Oliver et al.)...Overall, the chapters are well referenced and the book is well produced. It will serve as a useful point of departure to anyone contemplating novel applications of gene transfer technology, particularly in the less-studied fungi." Durgadas P. Kasbekar, The Quarterly Review of Biology


Contributors; Preface; 1. Gene-transfer systems and vector development for filamentous fungi C. A. M. J. J. van den Hondel and P. J. Hunt; 2. Strategies for cloning genes from filamentous fungi G. Turner; 3. Novel methods of DNA transfer J. W. Watts and N. J. Stacey; 4. Saccharomyces cerevisiae: a host for the production of foreign proteins J. E. Ogden; 5. The molecular biology of Trichoderma reesei and its application to biotechnology M. Pentila, T. T. Teeri, H. Nevalainen and J. K. C. Knowles; 6. Expression of heterologous genes in filamentous fungi R. W. Davies; 7. Methylotrophic yeasts as gene expression systems R. A. Veale and P. E. Sudbery; 8. Strain improvement of brewing yeast E. Hinchliffe; 9. Identification of the Cephalosporium acremonium pbcAB gene using predictions from an evolutionary hypothesis P. L. Skatrud, J. Hoskins, M. B. Tobin, J. R. Miller, J. S. Wood, S. Kovacevic and S. W. Queener; 10. Applications of genetically manipulated yeasts A. W. M. Strasser, Z. A. Janowicz, R. O. Roggenkamp, U. Dahlems, U. Weydemann, A. Merckelbach, G. Gellissen, R. J. Dohmen, M. Piontek, K. Melber and C. P. Hollenberg; 11. Molecular biology of fungal plant pathogenicity R. P. Oliver, M. L. Farman, N. J. Talbot and M. T. McHale; Index.

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