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About this book
About this book
Contents include: describes automated procedures used in microbiology and molecular biology; includes developments in robotics and vision systems; discusses paralogous duplications in microbial genomes; and describes and stresses the need for functional analysis.
L. Hood, Foreword. U. Pettersson, Introduction. A. Fife and D.W.M. Crook, Automation in Clinical Microbiology. A.J.McCollum, Vision Systems for Automated Colony and Plaque Picking. D.R. Bancroft, E. Maier and H. Lehrach, Library Picking, Presentation and Analysis. G. Kauer and H. Blocker, The PREPSEQ Robot: An Integrated Environment for Fully Automated and Unattended Plasmid Preparations and Sequencing Reactions. A.N. Hale, Building Realistic Automated Production Lines for Genetic Analysis. A.N. Hale, Examples of Automated Genetic Analysis Developments. L. Rowen, S. Lasky and L. Hood, Deciphering Genomes Through Automated Large-scale Sequencing. N.C. Hauser, M. Scheideler, S. Matysiak, M. Vingron and J.D. Hoheisel, DNA Arrays for Transcriptional Profiling. K.-J. Reiger, G. Orlowska, A. Kaniak, J.-Y. Coppee, G. Alijinovic and P.P. Slonimski, Large-scale Phenotypic Analysis in Microtitre Plates of Mutants with Deleted Open Reading Frames From Yeast Chromosome III: Key-step Between Genomic Sequencing And Protein Function. J.J. Codani, J.P. Comet, J.C. Aude, E. Glemet, A. Wozniak, J.L. Risler, A. Henaut and P.P. Slonimski, Automatic Analysis of Large-scale Pairwise Alignments of Protein Sequences. M.Y. Galperin and D. Frishman, Towards Automated Prediction of Protein Function from Microbial Genomic Sequences. Index.
Jorg D. Hoheisel received his Ph.D. in 1988 from the University of Konstanz, Germany, where he studied DNA structures. He was at the ICRF in London, UK from 1988 to 1993, working on genome analysis. Since 1993, he has been Head at the DKFZ (Deutsches Krebsforschungzentrum) in Heidelberg, Germany.
Handbook / Manual
270 pages, B/w photos, figs
Praise for the Volume "The editors have complied an impressive group of international investigators and experts in microbial and genomic automation, producing a text that clearly describes the present and future importance of automated protocol in biomedical research. This text should be read by all biomedical researchers..." --DOODY'S ELECTRONIC JOURNAL Praise for the Series "An invaluable resource for the detailed analysis of cellular gene function and genome architecture." --NATURE