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Academic & Professional Books  Organismal to Molecular Biology  Biochemistry & Molecular Biology

Biochemistry and Physiology of the Neutrophil

By: SW Edwards
300 pages, Illus
Biochemistry and Physiology of the Neutrophil
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  • Biochemistry and Physiology of the Neutrophil ISBN: 9780521416986 Hardback Mar 1994 Not in stock: Usually dispatched within 6 days
    £98.99
    #32306
Price: £98.99
About this book Contents Customer reviews Related titles

About this book

This book describes the role of the neutrophil in infection and inflammation and provides an up-to-date review of the biochemistry and physiology of this cell, highlighting the mechanisms by which they seek out and destroy pathogenic microorganisms. The development of these cells during haematopoiesis is described and the mechanisms that lead to the production of reactive oxidants and the intracellular signal transduction systems that lead to the cell's activation are reviewed. The book also discusses recent discoveries concerning the role of cytokines in the regulation of neutrophil function together with the importance of the neutrophil as a generator of inflammatory cytokines. Finally, there is a description of the biochemical defects that give rise to some of the neutrophil-associated human diseases.

Contents

1. Neutrophils and host defence: the fight against infection; 2. The development and structure of neutrophils; 3. The generation and recognition of neutrophil-activating factors: structure and function of neutrophil receptors; 4. The cytoskeleton: the molecular framework regulating cell shape and the traffic of intracellular components; 5. The respiratory burst: the generation of reactive oxygen metabolites and their role in microbial killing; 6. Neutrophil activation: the production of intracellular signalling molecules; 7. Neutrophil priming: regulation of neutrophil function during inflammatory activation; 8. Disorders of neutrophil function; Index.

Customer Reviews

By: SW Edwards
300 pages, Illus
Media reviews

...a useful basic reference and I would recommend it to immunologists, microbiologists, biochemists, physiologists, infectious disease specialists, hematologists, or to anyone whose interest lies in immunology or microbiology. John O. Naim, Immunological Investigations

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