Since its first edition in 1975, this extraordinary textbook has helped shape the way that biochemistry is taught, and has become one of the most trusted books in the field. It offers exceptionally clear writing, innovative graphics, coverage of the latest research techniques and advances, and a signature emphasis on physiological and medical relevance.
The seventh edition has been updated throughout, including many new advances on genetic regulation, and revamped coverage of the integration of metabolism in the context of diet and obesity. Numerous new medical examples have been added throughout to make biochemistry real and relevant to students. The addition of new contributing author Gregory Gatto, an active pharmaceutical researcher at GlaxoSmithKline, ensures that the seventh edition presents the latest techniques that students need to understand in biochemistry research today. The end-of-chapter problems have also been revised and updated, providing students with great new exercises to test their understanding.
The book is supported by a companion website which provides a variety of tools to aid understanding and learning including concept-based tutorials, animated techniques, self-assessment tools, and living figures that allow protein structures to be explored in 3-D.
PART I: THE MOLECULAR DESIGN OF LIFE
Biochemistry: An Evolving Science
Protein Composition and Structure
Exploring Proteins and Proteomes
DNA, RNA, and the Flow of Genetic Information
Exploring Genes and Genomes
Exploring Evolution and Bioinformatics
Hemoglobin: Portrait of a Protein in Action
Enzymes: Basic Concepts and Kinetics
Lipids and Cell Membranes
Membrane Channels and Pumps
PART II: TRANSDUCING AND STORING ENERGY
Metabolism: Basic Concepts and Design
Glycolysis and Gluconeogenesis
The Citric Acid Cycle
The Light Reactions of Photosynthesis
The Calvin Cycle and the Pentose Phosphate Pathway
Fatty Acid Metabolism
Protein Turnover and Amino Acid Catabolism
PART III: SYNTHESIZING THE MOLECULES OF LIFE
The Biosynthesis of Amino Acids
The Biosynthesis of Membrane Lipids and Steroids
The Integration of Metabolism
DNA Replication, Repair, and Recombination
RNA Synthesis and Processing
The Control of Gene Expression in Prokaryotes
The Control of Gene Expression in Eukaryotes
PART IV: RESPONDING TO ENVIRONMENTAL CHANGES
The Immune System
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Jeremy M. Berg is Director of the National Institute of General Medical Sciences at the National Institutes of Health, USA. He is the recipient of the American Chemical Society Award in Pure Chemistry (1994), the Eli Lilly Award for Fundamental Research in Biological Chemistry (1995), the Maryland Outstanding Young Scientist of the Year (1995) and the Harrison Howe Award (1997).
John L. Tymoczko is the Towsley Professor of Biology at Carleton College, USA, where he has taught since 1976.
Lubert Stryer is Winzer Professor of Cell Biology, Emeritus, in the School of Medicine and Professor of Neurobiology, Emeritus, at Stanford University.