Biology of Phosphoinositides

About this book

Review of the latest research in lipid signalling with the emphasis on the integration of the use of lipid signals in signal transduction and membrane trafficking.

Contents

Regulation of Phosphoinositide-specific Phospholipase C isozymes; Phosphoinositide- 3-kinases - Regulation by cell surface receptors and function of 3-phosphorylated lipids; Enzymes involved in the synthesis of phosphatidylinositol 4,5 bisphosphate and their regulation - Phosphoinositide kinases; Pleckstrin Homology Domains: Phosphoinositide-regulated membrane tethers; Regulation of cytoskeletal protein by inositol lipids; Physiological functions phosphatidylinositol transfer proteins; Glycosyl-phosphatidylinositol anchored proteins and their phospholipases; Phosphatidylinositol 3 kinase and membrane traffic; Regulation of Phospholipase D signalling by phosphoinositides; Regulation of chloride channel conductance by inositol (3,4,5,6) tetraphosphate; A phosphoinositide-initiated signalling pathway that acts downstream of inositol (1,4,5) trisphosphate; Phosphatases for inositol lipids and for inositol phosphates

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