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By: Sung-Hou Kim and Gregory E Sims
Molecular systematics - the organising and mapping of molecules - would have been very difficult a decade ago. It became possible because of the meeting of two factors - the availability of a vast amount of sequence and structural data of biomolecules and properties of organic chemicals and the dramatically increased computing power and computational algorithms developed to use such computing power.
This relatively new area of research has spawned a new discipline by bringing in biologists, computational scientists and mathematicians to answer key questions that cannot be obtained by any other approach. This book summarises the field, over the past two decades, in organising and mapping (for visualisation) protein space, nucleic acid space, and small molecule space in terms of their sequences and structures.
Chapter 1: Proteins; Chapter 2: Nucleic Acids; Chapter 3: Small Organic Molecule Mapping; Appendix
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Professor Sung-Hou Kim, University of California, Berkeley, CA, USA. Dr Gregory E Sims, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.
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