Global climate change - rapid, substantial and human-induced - may have radical consequences for life on earth. The problem is a complex one, however, demanding a multi-disciplinary approach. A simple cost-benefit analysis cannot capture the essentials, nor can the issue be reduced to an emissions reduction game, as the Kyoto process tries to do. This text considers an integrative approach, which reveals that global climate change needs to be considered as a spider in a web, a triggering factor for a range of other, related problems - land use changes, water supply and demand, food supply, energy supply, human health, and air pollution. But an approach like this, which takes account of all items of knowledge, known and uncertain, does not produce clear-cut, final and popular answers. It does provide useful insights, however, which will allow comprehensive and effective long-term climate strategies to be put into effect.