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The last quarter of the 20th century saw major scientific revolutions in genetics and computer technology. This book reflects this massive surge in our understanding of the molecular foundations of genetics. In order to understand where these technological advances are heading, there needs to be a basic understanding of how living organisms function at a molecular level. Molecular Biology, 2e, effectively introduces basic concepts followed by more specific applications as the text evolves. With the addition of Cell Press articles, the content is tied to current topics in the scientific community.
Unit 1: Basic Chemical and Biological Principles
Ch1 Cells and Organisms
Ch2 Basic Genetics
Ch3 DNA, RNA, and Protein
Ch4 Genes, Genomes, and DNA
Ch5 Manipulation of Nucleic Acids
Unit 2: The Genome
Ch6 Polymerase Chain Reaction
Ch7 Cloning Genes for Analysis
Ch8 DNA Sequencing
Ch9 Genomics & Systems Biology
Unit 3: The Central Dogma of Molecular Biology
Ch10 Cell Division and DNA Replication
Ch11 Transcription of Genes
Ch12 Processing of RNA
Ch13 Protein Synthesis
Ch14 Protein Structure & Function
Ch15 Proteomics: Global Analysis of Proteins
Unit 4: Regulating Gene Expression
Ch16 Regulation of Transcription in Prokaryotes
Ch17 Regulation of Transcription in Eukaryotes
Ch18 Regulation at RNA Level
Ch19 Analysis of Gene Expression (Transcriptome)
Unit 5: Subcellular Life Forms
Ch20 Plasmids
Ch21 Viruses
Ch22 Mobile DNA
Unit 6: Changing the DNA Blueprint
Ch23 Mutations and Repair
Ch24 Recombination
Ch25 Bacterial Genetics
Ch26 Molecular Evolution
Dr. Clark has taught courses in Molecular Biology and Bacterial Physiology and Biochemistry at Southern Illinois University since 1981. Research into the Regulation of Alcohol Fermentation in E. coli has been funded by the U.S. Department of Energy, Office of Basic Energy Sciences from 1982 till present. Supervised 11 master's and 7 PhD students Published approximately 70 articles in scientific journals Previously published work includes Molecular Biology Made Simple and Fun coauthored with Lonnie Russell.
