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Evolutionary genetics is concerned with nature of the variability used in evolution, and the causes of evolutionary change. The methods of evolutionary genetics are critically important for the analysis and interpretation of the massive datasets on DNA sequence variation and evolution that are becoming available, as well for our understanding of evolution in general.
This book highlights how models of the genetic processes involved in evolution are made (including natural selection, migration, mutation, and genetic drift in finite populations), and how the models are used to interpret classical and molecular genetic data.
1 Variability and its measurement
2 Basic selection theory and the maintenance of variation
3 Directional selection and adaptation
4 Migration, mutation and selection
5 The evolutionary effects of finite population size: basic theory
6 Molecular evolution and variation
7 Genetic effects of spatial structure
8 Multiple sites and loci
9 The evolution of breeding systems, sex ratios and life histories
10 Some Topics in Genome Evolution Mathematical and Statistical Appendix
Brian and Deborah Charlesworth obtained PhDs in genetics at Cambridge, and have subsequently worked at the Universities of Liverpool, Sussex, Chicago and Edinburgh.
The book by Charlesworth and Charlesworth provides an authoritative and accessible review of classical and modern population genetics. It can serve as a text for several graduate level courses and will be an invaluable reference to researchers in all areas of biology. -Montgomery Slatkin, University of California, Berkeley