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Eukaryotic DNA Replication: A Practical Approach

Handbook / Manual

Series: Practical Approach Series Volume: 199

Edited By: Sue Cotterill

281 pages, 10 b/w illus, 24 figs

Oxford University Press

Paperback | Feb 1999 | #90271 | ISBN: 019963680X
Availability: Usually dispatched within 5 days Details
NHBS Price: £79.99 $105/€89 approx
Hardback | Feb 1999 | #90270 | ISBN: 0199636818
Out of Print Details

About this book

Eukaryotic DNA Replication: A Practical Approach is a comprehensive practical manual, with each of its eleven chapters describing an aspect of the methods currently used to investigate DNA replication in eukaryotes. The sequence of the chapters corresponds roughly to the order of events during DNA replication. The first chapters are concerned with initiation, looking at methods to characterize origins of replication and the proteins that interact with them. There then follow chapters describing protocols for the study of the elongation phase and the synthesis of the telomeres. The final chapters provide a more general overview of the study of DNA replication - including its investigation in model systems such as yeast, xenopus and viruses, and looks into methods used to study DNA:protein interactions that could be applied to the study of replication proteins. This exciting new volume provides over 120 tried and tested protocols for the analysis of eukaryotic DNA replication and will be of major interest to a wide variety of molecular and cell biologists, biochemists and medical researchers.

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