To see accurate pricing, please choose your delivery country.
 
 
United States
£ GBP
All Shops

British Wildlife

8 issues per year 84 pages per issue Subscription only

British Wildlife is the leading natural history magazine in the UK, providing essential reading for both enthusiast and professional naturalists and wildlife conservationists. Published eight times a year, British Wildlife bridges the gap between popular writing and scientific literature through a combination of long-form articles, regular columns and reports, book reviews and letters.

Subscriptions from £33 per year

Conservation Land Management

4 issues per year 44 pages per issue Subscription only

Conservation Land Management (CLM) is a quarterly magazine that is widely regarded as essential reading for all who are involved in land management for nature conservation, across the British Isles. CLM includes long-form articles, events listings, publication reviews, new product information and updates, reports of conferences and letters.

Subscriptions from £26 per year
Academic & Professional Books  Organismal to Molecular Biology  Biochemistry & Molecular Biology

Eukaryotic mRNA Processing

Out of Print
Edited By: Adrian R Krainer
394 pages
Publisher: IRL Press
Eukaryotic mRNA Processing
Click to have a closer look
Select version
  • Eukaryotic mRNA Processing ISBN: 9780199634170 Paperback Aug 1997 Out of Print #84036
  • Eukaryotic mRNA Processing ISBN: 9780199634187 Hardback Dec 1997 Out of Print #84034
About this book Contents Related titles

About this book

This volume focuses on the major aspects of post-transcriptional mRNA processing in the nucleus of eukaryotic cells. Each of the described mRNA reactions is required for proper gene expression and can also serve as a control point for regulating the expression of many genes, for example during embryonic development or in different cell types. The different chapters review the assembly of newly synthesized nuclear mRNA transcripts into hnRNP particles and catalytically active spliceosomes; the structure and mechanism of action of small nuclear ribonucleoprotein particles and protein factors that catalyse pre-mRNA splicing in mammalian cells and in yeast; the regulation of gene expression and generation of protein isoform diversity by alternative splicing; the mechanisms of 3' end cleavage and polyadenylation; the architecture of the cell nucleus in relation to these processes and to the localization of the relevant substrates and factors; the diverse mechanisms of RNA processing by ribozymes and their potential relevance for nuclear mRNA processing; the mechanism of spliced-leader addition by trans-splicing in nematodes and trypanosomes; and the process of insertion/deletion mRNA editing in kinetoplasmid protozoa. In each chapter, leading researchers have provided detailed, critical reviews of the history, experimental approaches, major advances, current ideas and models, as well as future directions, for each of these active areas of research.

Contents

1. RNA-catalysed RNA processing; 2. Nuclear organization of pre-mRNA splicing factors and substrates; 3. The packaging of pre-mRNA; 4. Spliceosome assembly; 5. snRNP structure and function; 6. Mammalian pre-mRNA splicing factors; 7. Pre-mRNA splicing factors in the yeast Saccharomyces cerevisiae; 8. Alternative pre-mRNA splicing; 9. Capping, methylation, and 3'-end formation of pre-mRNA; 10. Trans-splicing; 11. mRNA editing

Customer Reviews

Out of Print
Edited By: Adrian R Krainer
394 pages
Publisher: IRL Press
Media reviews

"It was only 20 years ago that an mRNA was considered to be a hard-wired connector, faithfully transporting the linear genetic code from DNA to ribosomes. All this changed with the discovery of mRNA splicing in the late 1970s. The realization that the initial RNA transcript must be extensively processed prior to nuclear export and translation has opened up a whole new field of molecular biology--RNA processing. Research in this area has culminated in an appreciation for the full extent to which processing of an mRNA determines both its functional capacity and its coding potential. . . . [T]he chapters present and attempt to reconcile disparate findings and models. The writing is clear, references are copious, and the figures ... are useful adjuncts to the text. . . . The revolution in our understanding of eukaryotic mRNA biology brought on by the past 20 years of research on RNA processing is nicely captured, documented, and synthesized in this volume."--The Quarterly Review of Bio
Current promotions
New and Forthcoming BooksNHBS Moth TrapBritish Wildlife MagazineBuyers Guides