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The book describes in great detail the complex life cycle of fleas based on the example of the cat flea (Ctenocephalides felis), the most important ectoparasite worldwide. Besides being the cause of painfully itching bites and allergic skin diseases, it is also a vector for viruses, bacteria, nematodes and cestodes. Over the years the market for insecticide use in small animals has become a major segment of the chemical-pharmaceutical industry. Insecticides of the new generation should not only fight the existing infestation (therapy) but should also effectively prevent new infestations for weeks (prophylaxis). The latest class of chemicals developed to this effect are chloronicotinyls (syn. neonicotinoides). Imidacloprid is the first member of this class of insecticides with a high selectivity towards the site of action within an insect. Applied to the skin it combats flea infestation persistently. The book describes the development of the compound from its discovery to its use in veterinary medicine.
Introduction * General Morphology * Taxonomy * Dissemination and Economic, Veterinary and Medical Importance * Developmental Cycle of Fleas * Flea Epidemiology * Flea-Related Dermatitis: Flea Bite Dermatitis. Flea Allergy Dermatitis (FAD). Diagnosis of FAD and Flea Bite Dermatitis. Treatment of Flea-Related Skin Diseases. Treatment of the Premises * Resistance * Imidacloprid: History. Chemical Properties. Biological Profile, Mode of Action and Direct Insecticidal Activity. Indirect Insecticidal Effects. Resistance of Sucking Pests Against Imidacloprid. Toxicology and Pharmacology. Imidacloprid as a Veterinary Product for Flea Control * References * Subject Index.