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The 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genome-wide Association Studies, Family-based Association Studies, Pharmacogenetics, Epigenetics, Ethic and Insurance.
As with the second Edition, the Handbook includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. With heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research.
D. J. Balding Imperial College of Science, Technology and Medicine, London, UK M. Bishop CNR-ITB, Milan, Italy C. Cannings University of Sheffield, UK
A treasure house of information on genetics and statistical methods ... .All approaches are fully described and evaluated, which make this handbook a work of scholarship and a valuable resource. (Journal of Tropical Pediatrics, February 2009) "This handbook may be highly recommended as a reference book and as a comprehensive opportunity to get a broader overview of new research areas in the field of statistical genetics. It will be useful source especially for research groups in this area." (Biometrics, September 2008) "This highly recommended set is critical investment for academic and special libraries, given rapid developments in statistical genetics." (American Reference Books Annual, March 2008)