Herbal Medicines Development and Validation of Plant-derived Medicines for Human Health

About this book

While discussion concerning the validity of the plant approach to nutrition and disease treatment continues, the explosion of natural product use has generated concern regarding their effectiveness and possible danger. Using a rational, sequential approach, Herbal Medicines: Development and Validation of Plant-derived Medicines for Human Health explores the development of efficacious medicinal herbal products. Expert contributors from the fields of natural products research and drug discovery bring awareness to the many problems facing the development of such products, such as quality control, pharmacokinetic and pharmacodynamic issues. The text addresses botanical, phytochemical, PD-PK, as well as analytical and clinical issues.

Contents

- The European Legislation (Directive 2004/24/EC) Brings Clarification and Recognition to Herbal Medicinal Products, Giuseppe Nisticò and Dagmar Roth-Behrendt
- Taxonomy, Morphology, and Ecology of Medicinal Plants: A Botanical Perspective, Simon Pierce, Alessandra Luzzaro, and Bruno E. L. Cerabolini
- Ethnopharmacological Approaches Used to Identify Medicinal Plants, Tsukasa Sakurada, Hirokazu Mizoguchi, Soh Katsuyama,Takaakai Komatsu, Hikari Kuwahata, Laura Rombolá, Giacinto Bagetta, Maria Tiziana Corasaniti, and Shinobu Sakurada
- Medicinal Plants: Molecular Biology/Biotechnology Approach, Candida Vannini, Manuela Campa, Federica Sassi, and Marcella Bracale
- Breeding and Cultivation of Medicinal Plants, Christoph Carlen
- Sample Preparation, Analytical Methods and Chemical Standardization of Medicinal Plant, Angela Perrone, Sonia Piacente, Luca Rastrelli, and Giovanni Dugo
- The Role of Zebrafish in the Future of Natural Product Discovery, Alexander D. Crawford, Camila V. Esguerra, and Peter A. M. de Witte
- Phytocomplexes versus Single-Entity Drugs: The Never-Ending Dilemma in Herbal Medicine, Elizabeth M. Williamson
- Molecular Modes of Action of Drugs Used in Phytomedicine, Michael Wink
- Bioavailability Issues of Nonnutrient Plant and Fruit Constituents, Mariusz Konrad Piskula and Junji Terao
- From Identification to Clinical Translation of Medicinal Plants, Gian Franco Gensini, Luigi Gori, Alfredo Vannacci, and Fabio Firenzuoli
- Recommendations for Reporting Randomized Controlled Trials of Herbal Medicine Interventions, Joel J. Gagnier, Heather Boon, Paula Rochon, David Moher, Joanne Barnes, and Claire Bombardier
- Pharmacovigilance Methods and Systems in Herbal Medicines, Gioacchino Calapai
- Mechanisms and Clinical Relevance of Herb–Drug Interactions from the Perspectives of Pharmacokinetics, Laura Berliocchi, Rossella Russo, Hirokazu Mitsoguchi, and Maria Tiziana Corasaniti
- Nature’s Gift to Photodynamic Medicine: Hypericin, a Herbal Photosensitizer, is a Component of Hypericum Perforatum, Heinrich Walt
- Plants and Plant-Derived Products as Cancer Chemopreventive Agents, Douglas M. Noonan, Ilaria Sogno, and Adriana Albini
- From Standard Tanacetum Parthenium Extract to a Stabilized Derivative of Parthenolide: Studies in Animal Models of Pain, Rosaria Greco, Cristina Tassorelli, Antonina Stefania Mangione, Paolo Morazzoni, Ezio Bombardelli, and Giuseppe Nappi
- Antiviral Effects of Essential Oils Used Traditionally in Phytomedicine
- Jürgen Reichling and Paul Schnitzler
- The Neuroprotective Capacity of Achyrocline Satureioides (Lam) D.C. and its Flavonoids: Mechanisms of Action, Federico Dajas, Juan A. Abin-Carriquiry, Florencia Arredondo, Fernanda Blasina, Marcela Diaz, Carolina Echeverry, Felicia Rivera-Megret, and Lucia Vaamonde
- Recent Progress in Echinacea Research, Karin Woelkart and Rudolf Bauer
- Contribution of Herbal Medicine to Human Health: A Brief History, Luigi Antonio Morrone, Laura Rombolà, Diana Amantea, Hirokazu Mizoguchi, and Maria Tiziana Corasaniti
- Quality Issues of Current Herbal Medicines, Paola Montoro, Sonia Piacente, and Cosimo Pizza
- Herbal Medicines in the Developing World: South America, Federico Dajas and Felicia Rivera-Megret
- Herbal Medicines: Epidemiology of their Utilization—A Perspective on the Industrialized World, Anna Loraschi and Marco Cosentino

Index

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