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About this book
About this book
There has been a growing interest in exploring the role of lycopene in the prevention of a variety of nutritional and health issues in humans, including some cancers and cardiovascular diseases. Recently, many case studies using cell cultures, animal models, and epidemiological investigations have shown a relationship between lycopene intake and a lowered risk of contracting some cancers and various chronic diseases.
Increasingly, clinical evidence supports the role of lycopene as a nutrient with important health benefits, since it appears to provide protection against a broad range of epithelial cancers. The possibility that consumption of lycopene-rich foods may reduce the risk of such diseases has prompted numerous in-depth studies of the levels of lycopene in foods and of correlations between dietary lycopene and certain diseases.This monograph will serve as a reference for providing a better understanding of the role of lycopene in promoting health, and by encouraging a deeper understanding of approaches to a healthy diet and life.
Part 1: Characterization of Lycopene from Chemistry to Basic Physiological Functions; Lycopene Overview: What it is and What it Does: Robert M. Diener and Mildred S. Christian; Stability of Lycopene During Food Processing and Storage: John Shi and Sophia Jun Xue; Lycopene Metabolites: Apo-lycopenals: Nikki A. Ford and John W. Erdman, Jr.; Non-covalent Binding of Lycopene and Lycophyll: Zsolt Bikadi, Peter Hari, Eszter Hazai, Samuel F. Lockwood and Ferenc Zsila; Risk Assessment of Lycopene: Andrew Shao and John N. Hathcock; Part 2: Biochemical and Physiological Features of Lycopene's Effects; Lycopene and Peroxynitrite Modifications: Kaampwe Muzandu, Kennedy Choongo and Shoichi Fujita; Lycopene and Down-regulation of Cyclin D1, pAKT and pBad: Rosanna Sestito and Paola Palozza; Lycopene and Chylomicrons: Kathleen M. Botham and Elena Bravo; Lycopene and Chromosomal Aberrations: Lusania Maria Greggi Antunes and Maria de Lourdes Pires Bianchi; Lycopene and Lycopene-enriched Prostasomes: A. Goyal, M. Chopra and Alan Cooper. Topically Applied Lycopene and Antioxidant Capacity: Marco Andreassi and Lucio Andreassi; Lycopene and Cardiovascular Diseases: Martha Verghese, Rajitha Sunkara, Louis Shackelford and Lloyd T. Walker; Effects of Lycopene and Monounsaturated Fat Combination on Serum Lycopene, Lipid and Lipoprotein Concentrations: K.D.K. Ahuja, Madeleine Joyce Ball and Merran Rogers; Lycopene: Cataract and Oxidative Stress: S.K. Gupta, S. Srivastava, R. Agarwal and S.S. Agrawal; Lycopene and Bone Tissue: L.G. Rao and E.S. Mackinnon; Part 3: Lycopene and Cancer; Lycopene and Its Potential Role in Prostate Cancer Prevention: A. Trion, F.H. Schroder and W.M. van Weerden; Lycopene and Urokinase Receptor Expression in Prostate Cancer Cells: I. Sehgal D.V.M.; Lycopene and Lung Cancer: Fuzhi Lian and Xiang-Dong Wang; Breast Cancer and Lycopene: Nassera Chalabi, Yves-Jean Bignon and Dominique J. Bernard-Gallon; Lycopene and Colon Cancer: Martha Verghese, Judith Boateng, Louis Shackelford and Lloyd T. Walker.