Books  Ecological & Biological Sciences  Environmental Science  Toxicology 

Modelling Environmental Fate and Toxicity

Edited By: Mark Cronin and David Livingstone

320 pages, 60 b/w illus, 5 col photos, 30 tabs

Taylor & Francis

Hardback | Dec 2003 | #141716 | ISBN: 0415271800
Availability: Usually dispatched within 6 days Details
NHBS Price: £86.00 $112/€98 approx

About this book

Quantitative Structure-Activity Relationships (QSARs) are increasingly used to predict the effects of chemicals in the environment. This increased use has come from a variety of areas - academics, industrial, regulatory - and has been spawned from a realisation that there are very few toxicological data for the vast numbers of chemicals released into the environment.


Contents

INTRODUCTIONPredicting Chemical Toxicity and Fate in Humans and the Environment - An IntroductionMETHODOLOGYToxicity Data SourcesCalculation of Physicochemical PropertiesGood Practice in Physicochemical Property PredictionWhole Molecule and Atom Based Topological DescriptorsQuantum Chemical Descriptors in Structure-Activity Relationships - Calculation, Interpretation and comparison of MethodsBuilding QSAR Models - A Practical GuideQSARs FOR HUMAN HEALTH ENDPOINTSPrediction of Human Health Endpoints: Mutagenicity and CarcinogenicityThe Use of Expert Systems for Toxicity Prediction - Illustrated with Reference to the DEREK ProgramComputer-Based Methods for the Prediction of Chemical Metabolism and Biotransformation within Biological OrganismsPrediction of Pharmacokinetic Parameters in Drug Design and ToxicologyQSARs FOR ENVIRONMENTAL TOXICITY AND FATEAn Exercise in External Validation: The Benzene Response-Surface Model for Tetrahymena ToxicityReceptor-Mediated Toxicity: QSARs for Oestrogen Receptor Binding and Priority Setting of Potential Oestrogenic Endocrine DisruptorsPrediction of PersistenceQSAR Modelling of BioaccumulationQSAR Modelling of Soil SorptionApplication of Catabolic-Based Biosensors to Develop QSARs for DegradationAPPLICATIONThe Tiered Approach to Toxicity Assessment Based on the Integrated Use of Alternative (Non-Animal) TestsThe Use of Quantitative Structure-Activity Relationships and Expert Systems to Predict Toxicity by Governmental Regulatory AgenciesA Framework for Promoting the Acceptance and Regulatory Use of (Quantitative) Structure-Activity Relationships.

Write a review

There are currently no reviews for this book. Be the first to review this book!

Bestsellers in this subject

Human and Ecological Risk Assessment

NHBS Price: £128.00 $167/€145 approx

Principles of Ecotoxicology

NHBS Price: £43.99 $57/€50 approx

Wildlife Toxicology

NHBS Price: £96.99 $127/€110 approx

Ecotoxicology Essentials

NHBS Price: £54.99 $72/€62 approx

The Toxicology and Biochemistry of Insecticides

NHBS Price: £50.99 $67/€58 approx

VAT: GB 407 4846 44
NHBS Ltd is registered in England and Wales: 1875194