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Natural Products Isolation: Second Edition presents a practical overview of just how natural products can be extracted, prepared, and isolated from the source material. Maintaining the main theme and philosophy of the first edition, this second edition incorporates all the new significant developments in this field of research. The chapters are divided into four distinct sections: introduction, extraction, chromatography, and special topics.
This second edition provides substantial backround information for natural product researchers and will prove a useful reference guide to all of the available techniques.
Natural Product Isolation: An Overview. Initial and Bulk Extraction. Supercritical Fluid Extraction. An Introduction to Planar Chromatography. Isolation of Natural Products by Low-Pressure Column Chromatography. Isolation by Ion-Exchange Methods. Separation by High-Speed Countercurrent Chromatography. Isolation by Preparative High-Performance Liquid Chromatography. Hyphenated Techniques. Purification by Solvent Extraction Using Partition Coefficient. Crystallization in Final Stages of Purification. Dereplication and Partial Identification of Compounds. Extraction of Plant Secondary Metabolites. Isolation of Marine Natural Products. Isolation of Microbial Natural Products. Purification of Water-Soluble Natural Products. Scale-Up of Natural Product Isolation. Follow-Up of Natural Product Isolation. Index.
... offers extensive help in the selection of a suitable methodology...an excellent aid...closes a painfully evident gap in the selection of monographs on natural products chemistry...warmly recommended to anyone interested in the isolation of natural products. - Angewandte Chemie