About this book
Provides an invaluable reference source of general viral concepts and specific viral systems, providing an excellent foundation to our understanding of how viruses emerge.
Contents
P. Schuster and P.F. Stadler, Nature and Evolution of Early Replicons. H.D. Robertson and O.D. Neel, Virus Origins: Conjoined RNA Genomes as Precursors to DNA Genomes. J.S. Semancik and N. Duran-Vila, Viroids in Plants: Shadows and Footprints of a Primitive RNA. C. Biebricher, Mutation, Competition, and Selection as Measured with Small RNA Molecules. A. Meyerhans and J.-P. Vartanian, The Fidelity of Cellular and Viral Polymerases and Its Manipulation for Hypermutagenesis. S. Wain-Hobson and M. Sala, Drift and Conservatism in RNA Virus Evolution: Are They Adapting or Merely Changing? E. Domingo, C. Escarmis, L. Menendez-Aarias, and J.J. Holland, Viral Quasispecies and Fitness Variations. M.A. McClure, The Retroid Agents: Disease, Function, and Evolution. D. Wodarz and M.A. Nowak, Dynamics of HIV Pathogenesis and Treatment. I.M. Rouzine and J.M. Coffin, Interplay between Experiment and Theory in Development of a Working Model for HIV-1 Population Dynamics. A.J. Gibbs, P.L. Keese, M.J. Gibbs, and F. Garcia-Arenal, Plant Virus Evolution: Past, Present, and Future. M. Gromeier, E. Wimmer, and A.E. Gorbalenya, Genetics, Pathogenesis, and Evolution of Picornaviruses. J.I. Esteban, M. Martell, W.F. Carman, and J. Gomez, The Impact of Rapid Evolution of the Hepatitis Viruses. R.G. Webster, Antigenic Variation in Influenza Viruses. L.P. Villarreal, DNA Virus Contribution to Host Evolution. C.R. Parrish and U. Truyen, Parvovirus Variation and Evolution. D.J. McGeoch and A.J. Davison, The Molecular Evolutionary History of the Herpesviruses. J. Salas, M.L. Salas, and E. Vinuela, African Swine Fever Virus: A Missing Link Between Poxviruses and Iridoviruses? Subject Index.
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Biography
Esteban Domingo studied chemistry and biochemistry at the University of Barcelona, Spain and spent postdoctoral stays at the University of California, Irvine and the University of Zurich. His main interests are the quasispecies structure of RNA viruses and the development of new antiviral strategies. He is presently Professor of Research of the Spanish Research Council (CSIC) at Centro de Biologia Molecular "Servero Ochoa" in Madrid. Dr. Robert Webster has worked in the field of Virology for over 30 years, first in New Zealand and then at the John Curtin School of Medical Research in Australia. He has spent the past 25 years at St. Jude Childrens Research Hospital in the Department of Virology & Molecular Biology. In addition to his position as Chairman at St. Jude, Dr. Webster is Director of the U.S. Collaborating Center of the World Health Organization dealing with the ecology of animal influenza viruses. He has served on numerous national and international advisory boards and is a Fellow of the Royal Society. Dr. Webster has published extensively on influenza in areas covering the origin of pandemic strains, genetic variation, structure and function of virus and, in conjunction with Graeme Laver, was responsible for the development of influenza subunit vaccines.
