All Shops

Go to British Wildlife

6 issues per year 84 pages per issue Subscription only

British Wildlife is the leading natural history magazine in the UK, providing essential reading for both enthusiast and professional naturalists and wildlife conservationists. Published six times a year, British Wildlife bridges the gap between popular writing and scientific literature through a combination of long-form articles, regular columns and reports, book reviews and letters.

Subscriptions from £25 per year

Conservation Land Management

4 issues per year 44 pages per issue Subscription only

Conservation Land Management (CLM) is a quarterly magazine that is widely regarded as essential reading for all who are involved in land management for nature conservation, across the British Isles. CLM includes long-form articles, events listings, publication reviews, new product information and updates, reports of conferences and letters.

Subscriptions from £18 per year
Academic & Professional Books  Organismal to Molecular Biology  Biochemistry & Molecular Biology

Prokaryotic Toxin-Antitoxins

By: Kenn D Gerdes(Editor)
484 pages, 69 colour & 8 b/w illustrations, 3 colour tables
Publisher: Springer-Verlag
Prokaryotic Toxin-Antitoxins
Click to have a closer look
Select version
  • Prokaryotic Toxin-Antitoxins ISBN: 9783642332524 Hardback Oct 2012 Usually dispatched within 1-2 weeks
    £179.99
    #201913
Selected version: £179.99
About this book Contents Customer reviews Related titles

About this book

Prokaryotic Toxins – Antitoxins gives the first overview of an exciting and rapidly expanding research field. Toxin – antitoxin (TA) genes were discovered on plasmids 30 years ago. Since then it has become evident that TA genes are highly abundant in bacterial and archaeal chromosomes. TA genes code for an antitoxin that combine with and neutralize a cognate toxin.

When activated, the toxins inhibit protein synthesis and cell growth and thereby induce dormancy and multidrug tolerance (persistence). Remarkably, in some species, the TA gene families have undergone dramatic expansions. For example, the highly persistent major human pathogen Mycobacterium tuberculosis has A"100 TA loci.

The large expansion of TA genes by some organisms is a biological mystery. However, recent observations indicate that TA genes contribute cumulatively to the persistence of bacteria. This medically important phenomenon may thus for the first time become experimentally tractable at the molecular level.

Contents

Introduction.- Type I Toxin - Antitoxin Systems: Hok/Sok and Fst .- Novel Type I Toxin - Antitoxin Systems.- Type II TA Loci: The Ccdab and Parde Families.- Type II TA Loci: The Relbe Family.- Type II TA Loci: The Unusual Mqsra Locus.- Type II TA Loci: The Mazef Family.- Type II TA Loci: Vapbc and Other TA Loci In Mycobacteria.- Type II TA Loci: Phd Doc Family.- Type II TA Loci: The Fic Family.- Type II TA Loci, Hipab And Persisters.- Type II TA Loci: Zeta/Pezt Family.- Type II Loci: Phylogeny.- Type III TA Loci.- TA Loci Encoded By Plasmids.- TA Loci in Archaea.- TA Loci in Mycobacterium Tuberculosis.- TA Loci in Streptococcus Pneumoniae.- Biotechnological and Medical Exploitations Of TA Genes and Their Components.

Customer Reviews

By: Kenn D Gerdes(Editor)
484 pages, 69 colour & 8 b/w illustrations, 3 colour tables
Publisher: Springer-Verlag
Current promotions
Best of Winter 2018Handbook of the Bees of the British Isles (2-Volume Set)Order your free copy of our 2018 equipment catalogueBritish Wildlife