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The first-ever comprehensive overview of the methods used in this key technology in modern biology provides the latest working knowledge needed by every scientist entering this growing field. It covers all the current technology and application areas, from microscopy and spectroscopy to proteomics and microfluidics.
INTRODUCTION Single Cell Analysis and Systems Biology Molecular Biology of the Single Cell IMAGING Single Cell Electron Tomography Single Molecule Fluorescence Monitoring in Cells Imaging Cell Surface with AFM Single Cell Fluorescence Imaging and Dynamics TECHNOLOGIES Single Cell Proteomics Microfluidic Single Cell Analytics Single Cell MALDI Microfluidic Single Cell Bioreactors Analytical Tools for Single Cells Optical Stretcher for Single Cells APPLICATIONS Single Cell Immunogenetics Cellular Astronomy Microgenomics of Virus-Host Interactions Single Cell Heterogeneity Genome and Transcriptome Analysis of Single Tumor Cells
Dario Anselmetti holds the chair in Experimental Biophysics and Applied Nanosciences at Bielefeld University (Germany). He obtained his academic degrees in Physics, Mathematics and Astronomy from Basel University (Switzerland), before becoming a post-doc at the IBM Research Laboratories. Later on, he worked for six years in the research department of Ciba-Geigy (now Novartis) as a project leader in nanobiophysics. After co-managing the Solvias spin-off company in Basel, he returned to academia, taking up his current position in 2000. Dr. Anselmetti has authored over 100 scientific publications and is a member of the Academy of Sciences of the state of Nordrhein-Westfalen.