All Shops

Go to British Wildlife

6 issues per year 84 pages per issue Subscription only

British Wildlife is the leading natural history magazine in the UK, providing essential reading for both enthusiast and professional naturalists and wildlife conservationists. Published six times a year, British Wildlife bridges the gap between popular writing and scientific literature through a combination of long-form articles, regular columns and reports, book reviews and letters.

Subscriptions from £25 per year

Conservation Land Management

4 issues per year 44 pages per issue Subscription only

Conservation Land Management (CLM) is a quarterly magazine that is widely regarded as essential reading for all who are involved in land management for nature conservation, across the British Isles. CLM includes long-form articles, events listings, publication reviews, new product information and updates, reports of conferences and letters.

Subscriptions from £18 per year
Academic & Professional Books  Organismal to Molecular Biology  Genetics

Statistical Approaches to Gene × Environment Interactions for Complex Phenotypes

Handbook / Manual
By: Michael Windle(Editor)
304 pages, 43 b/w illustrations
Publisher: MIT Press
Statistical Approaches to Gene × Environment Interactions for Complex Phenotypes
Click to have a closer look
Select version
  • Statistical Approaches to Gene × Environment Interactions for Complex Phenotypes ISBN: 9780262034685 Hardback Jul 2016 Usually dispatched within 4 days
    £39.99
    #237563
Selected version: £39.99
About this book Customer reviews Biography Related titles

About this book

Findings from the Human Genome Project and from Genome-Wide Association (GWA) studies indicate that many diseases and traits manifest a more complex genomic pattern than previously assumed. These findings, and advances in high-throughput sequencing, suggest that there are many sources of influence – genetic, epigenetic, and environmental. Statistical Approaches to Gene × Environment Interactions for Complex Phenotypes investigates the role of the interactions of genes and environment (G × E) in diseases and traits (referred to by the contributors as complex phenotypes) including depression, diabetes, obesity, and substance use.

The contributors first present different statistical approaches or strategies to address G × E and G × G interactions with high-throughput sequenced data, including two-stage procedures to identify G × E and G × G interactions, marker-set approaches to assessing interactions at the gene level, and the use of a partial-least square (PLS) approach. The contributors then turn to specific complex phenotypes, research designs, or combined methods that may advance the study of G × E interactions, considering such topics as randomized clinical trials in obesity research, longitudinal research designs and statistical models, and the development of polygenic scores to investigate G × E interactions.

Customer Reviews

Biography

Michael Windle is Professor of Public Health in the Department of Behavioral Sciences and Health Education at Emory University.


Contributors:
- Fatima Umber Ahmed
- Yin-Hsiu Chen
- James Y. Dai
- Caroline Y. Doyle
- Zihuai He
- Li Hsu
- Shuo Jiao
- Erin Loraine Kinnally
- Yi-An Ko
- Charles Kooperberg
- Seunggeun Lee
- Arnab Maity
- Jeanne M. McCaffery
- Bhramar Mukherjee
- Sung Kyun Park
- Duncan C. Thomas
- Alexandre Todorov
- Jung-Ying Tzeng
- Tao Wang
- Michael Windle
- Min Zhang

Handbook / Manual
By: Michael Windle(Editor)
304 pages, 43 b/w illustrations
Publisher: MIT Press
Current promotions
Backlist BargainsThe Mammal SocietyOrder your free copy of our 2018 equipment catalogueBritish Wildlife