Books  Ecological & Biological Sciences  Environmental Science  Toxicology 

Temperature and Toxicology: An Integrative, Comparative, and Environmental Approach

By: CJ Gordon

224 pages, Col & b/w illus

CRC Press

Hardback | Dec 2004 | #151821 | ISBN: 0849330246
Availability: Usually dispatched within 6 days Details
NHBS Price: £74.99 $98/€85 approx

About this book

Thermoregulation is vital for survival but the interplay between toxic insults and thermoregulatory mechanisms is often poorly understood. "Temperature and Toxicology: An Integrative, Comparative, and Environmental Approach" is the first major text to study the integrative thermoregulatory responses of mammals that are exposed to toxicants. Because environmental physiology is also crucial in toxicological responses, this volume also examines the role of environmental temperature in the modulation of cellular mechanisms of toxicity. The book begins by explaining the importance of temperature in toxicological studies, and how all biological processes are dependent on temperature. It then reviews the basics of temperature regulation in homeotherms and poikilotherms, and addresses whole-animal and in vitro studies related to the effects of temperature on toxicity. The text examines thermoregulatory response to toxic insult, and how responses affect recovery and potential survival. It describes hypothermic response in rodents to febrile and hyperthermic reactions in humans, and discusses the relevance of heat and cold stress on human exposures to airborne pollutants and other toxicants. This volume provides an extensive comparison of physiological responses of invertebrates, fish, amphibians, and mammals, and focuses on the impact of endocrine disruption. It then considers how toxicants and thermal stress cause the expression of stress proteins, followed by a study of the impact of genetic variability. The book concludes with an examination of thermoregulatory response to natural toxins and venoms.


Introduction. Principles of temperature regulation. Acute toxic thermoregulatory responses. Temperature effects on chemical toxicity. Regulated hypothermia: An adaptive response to toxic insult. Fever and hyperthermia. Environmental stress. Comparative physiological responses. Genetic variability and molecular markers. Toxins and venoms.

Write a review

There are currently no reviews for this book. Be the first to review this book!

Bestsellers in this subject

Human and Ecological Risk Assessment

NHBS Price: £128.00 $168/€145 approx

Principles of Ecotoxicology

NHBS Price: £43.99 $58/€50 approx

Wildlife Toxicology

NHBS Price: £96.99 $127/€110 approx

Ecotoxicology Essentials

NHBS Price: £54.99 $72/€62 approx

The Toxicology and Biochemistry of Insecticides

NHBS Price: £50.99 $67/€58 approx

VAT: GB 407 4846 44
NHBS Ltd is registered in England and Wales: 1875194