All Shops

Go to British Wildlife

6 issues per year 84 pages per issue Subscription only

British Wildlife is the leading natural history magazine in the UK, providing essential reading for both enthusiast and professional naturalists and wildlife conservationists. Published six times a year, British Wildlife bridges the gap between popular writing and scientific literature through a combination of long-form articles, regular columns and reports, book reviews and letters.

Subscriptions from £25 per year

Conservation Land Management

4 issues per year 44 pages per issue Subscription only

Conservation Land Management (CLM) is a quarterly magazine that is widely regarded as essential reading for all who are involved in land management for nature conservation, across the British Isles. CLM includes long-form articles, events listings, publication reviews, new product information and updates, reports of conferences and letters.

Subscriptions from £18 per year
Academic & Professional Books  Environmental & Social Studies  Economics, Politics & Policy  Health & Health Care

Thalassaemia: The Biography

By: David Weatherall
256 pages, approx 15 b/w illustrations
Thalassaemia: The Biography
Click to have a closer look
Select version
  • Thalassaemia: The Biography ISBN: 9780199565603 Hardback Aug 2010 Usually dispatched within 5 days
    £14.99
    #182872
Selected version: £14.99
About this book Contents Customer reviews Related titles

About this book

Thalassaemia is the most common type of genetic disorder in the human population, and one of the first whose genetic basis was established. Written by Sir David Weatherall, an expert in molecular medicine and the founder of the Institute of Molecular Medicine in Oxford, this tells the story of early reports of the disease, historical accounts, the identification of the disease as having an inherited basis, early work on thalassaemia as a disorder of the synthesis of haemoglobin, and from the 1960s with the rise of molecular biology, the study of the condition at the DNA level. The commonality of the disease raised an important evolutionary question: if thalassaemia is a genetic disorder then why hasn't it been selected out? Why does it persist, especially in Mediterranean populations? The great geneticist JBS Haldane suggested a reason - that carriers might be more resistant to malaria. Now that we have much more detailed understanding of the molecular basis of this set of diseases, has Haldane proved to be right? Weatherall shows that Haldane turns out to have been partially right. The book ends with recent improvements in treatment that have transformed patients' lives and a general assessment of how molecular approaches are impacting on medicine. Thalassaemia: the biography is part of the Oxford series, Biographies of Disease, edited by William and Helen Bynum. In each individual volume an expert historian of medicine tells the story of a particular disease or condition throughout history - not only in terms of growing medical understanding of its nature and cure, but also shifting social and cultural attitudes, and changes in the meaning of the name of the disease itself.

Contents

Prologue; 1. Beginnings: 1920 - 1935; 2. Thalassaemia is an extremely common genetic disease: 1935 - 1950; 3. Thalassaemia as a genetic disorder of haemoglobin production: 1950 - 1960; 4. Defective haemoglobin synthesis in thalassaemia and speculations about its molecular basis: 1960 - 1974; 5. The molecular era and the birth of molecular medicine: 1975 - 2000; 6. Was Haldane right?; 7. Lessons for the biomedical sciences; Glossary; Further Reading

Customer Reviews

By: David Weatherall
256 pages, approx 15 b/w illustrations
Current promotions
Best of Winter 2018Handbook of the Bees of the British Isles (2-Volume Set)Order your free copy of our 2018 equipment catalogueBritish Wildlife