About this book
Addresses every aspect of the field, starting with the fundamentals and incorporating such areas as organ toxicology, applications, and environmental toxicology.
Contents
H. Marquardt and S. Schafer, Foreword. Fundamentals: D. Milles, History of Toxicology. L. Hothorn and G. Hajian, Biostatistics in Toxicology. B. Fichtl, Toxicokinetics. F. Oesch and M. Arand, Xenobiotic Metabolism. M. Younes, Free Radicals and Reactive Oxygen Species. D. Brusick, Genetic Toxicology. H. Marquardt, Chemical Carcinogenesis. R. Schulte-Hermann, B. Marian, and W. Bursch, Tumor Promotion. K. Tindall and R. Tennant, Transgenic Rodent Models. J.-A. Gustafsson and C. Corton, Receptor Biology and Pathobiology. D. Polka, Mechanisms of Toxicity: Programmed Cell Death (Apoptosis). J.P. Groton, P.J. van Bladeren, F.R. Cassee, C. De Rosa, and V. Feron, Mixtures. Organtoxicity: R. Kahl, The Liver. C. Cojocel and E. Lock, The Kidney. H. Muhle and R. McClellan, Respiratory Tract. P. Eyer and R. Klimmek, Blood and Blood Forming Organs. D. Neubert, Immune System. J. Riviere and N. Montiero-Riviere, Skin Toxicology. R. Pfeiffer, Eye. D. Ray and K. Andreas, Nervous System. D. Neubert and F. Welsch, Reproduction and Development. J. Thomas and M. Thomas, Endocrine System-Adrenal Cortex Thyroid and Pancreas. K. Schumann, B. Elsenhans, and E. Richter, Gastrointestinal Tract. P. Boor, Cardiovascular Toxicology. Toxicology of Compounds: G. Koss and I. Tesseraux, Hydrocarbons. H. Bolt and J. Borlak, Halogenated Hydrocarbons. S. Magda, Flurohydrocarbons. E. Rose, E. Hodgson, and M. Roe, Pesticides. G. Koss and D. Wolfe, Dioxin and Dioxin-like Polychlorinated Hydrocarbons and Biphenyls. E. Richter and G. Sabbioni, Aromatic Amines, Nitroarenes and Heterocyclic Aromatic Amines. W. Kohl and G. Eisenbrand, N-Nitroso Compounds. S. Schaferwq, B. Elsenhans, R.L.F. Dawes, K. Schumann, and W. Forth, Metals. P. Eyer, Gases. D. Warheit, T. Hesterberg, and G. Hart, Fiber Toxicology. L. Szinicz and S. Baskin, Chemical and Biological Agents. D. Hoffmann and E. Wynder, Active and Passive Smoking. J. Corbett, W. Dressler, and R. Sharma, Cosmetics. E. Loser and G. Stropp, Polymers. U. Hagen, R.J. Preston, R. Fry, and J. Kummermehr, Radiation. J. Westendorf, The Toxicology of Natural Compounds. H. Bigalke and H. Wellhoner, Bacterial Toxins. Application of Toxicology: H.W. Rudiger, Biomonitoring and Occupational Medicine. Environmental Toxicology: R. Bull, Water. D.J. Paustenbach and T. Rodrigues, The Role of Toxicology and Risk Assessment in Environmental Remediation. Krekeler, Ecotoxicology. Hattan and A. Rulis, Food Toxicology. Gelbke, B. Hildebrand, and E. Kerfoot, Toxicological Evaluation Methods for the Registration of Chemicals. H. Spielmann, Alternatives in Toxicological Testing. A. Somogyi, Regulatory Toxicology. Risk Assessment: D. Neubert and R. Conolly, Possibilities and Methods of Quantitative Risk Assessment. S. Safe, Toxicity Equivalents and Their Use in Hazard and Risk Assessment. Appendix: I. Ollroge, Threshold Values and Recommendations. H. Marquardt and S. Schafer, Addresses of Toxicology Center and Information Sources.
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Biography
Dr. Seigfried Schafer and Dr. Hans. Marquardt are the editors of the very successful German edition of Toxicology. Dr. Seigfried Schafer and Dr. Hans Marquardt are the editors of the very successful German edition of Toxicology. Dr. Roger O. McClennan is president and CEO of the very highly regarded and respected non-profit Chemical Industry Institute of Toxicology. CIIT conducts research directed toward reducing the uncertainties in assessing human health risks of exposures to chemicals. Frank Welsch is a senior scientist at the very highly regarded and respected non-profit Chemical Industry Institute of Toxicology. CIIT conducts research directed toward reducing the uncertainties in assessing human health risks of exposures to chemicals.