Biology of Aging, Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. Biology of Aging also includes end-of-chapter discussion questions to help students assess their knowledge of the material.
- Basic Concepts in the Biology of Aging
- Measuring Biological Aging
- Evolutionary Theories of Longevity and Aging
- Cellular Aging
- Genetics of Longevity
- Plant Senescence
- Human Longevity and Life Span
- Common Functional Loss Associated with Aging
- Common Time-Dependent Disease in Humans
- Modulating Human Aging and Longevity
- Implications of an Extended Healthspan
Roger McDonald received his Ph.D. from the University of Southern California and is Professor Emeritus in the Department of Nutrition at the University of California, Davis. Dr. McDonald’s research focused on mechanisms of cellular aging and the interaction between nutrition and aging. His research addressed two key topics in the field: the relationship between dietary restriction and lifespan, and the effect of aging on circadian rhythms and hypothalamic regulation.