Books  Data Analysis & Modelling  Data Analysis & Statistics 

Computational Molecular Evolution

Series: Oxford Series in Ecology and Evolution (OSEE)

By: Ziheng Yang

355 pages, 96 illus

Oxford University Press

Paperback | Oct 2006 | #159811 | ISBN: 0198567022
Availability: Usually dispatched within 5 days Details
NHBS Price: £51.99 $73/€59 approx
Hardback | Oct 2006 | #159812 | ISBN: 0198566999
Availability: Usually dispatched within 2-3 weeks Details
NHBS Price: £110.00 $154/€125 approx

About this book

The field of molecular evolution has experienced explosive growth in recent years due to the rapid accumulation of genetic sequence data, continuous improvements to computer hardware and software, and the development of sophisticated analytical methods. The increasing availability of large genomic data sets requires powerful statistical methods to analyse and interpret them, generating both computational and conceptual challenges for the field.

Computational Molecular Evolution provides an up-to-date and comprehensive coverage of modern statistical and computational methods used in molecular evolutionary analysis, such as maximum likelihood and Bayesian statistics. Yang describes the models, methods and algorithms that are most useful for analysing the ever-increasing supply of molecular sequence data, with a view to furthering our understanding of the evolution of genes and genomes. The book emphasizes essential concepts rather than mathematical proofs. It includes detailed derivations and implementation details, as well as numerous illustrations, worked examples, and exercises. It will be of relevance and use to students and professional researchers (both empiricists and theoreticians) in the fields of molecular phylogenetics, evolutionary biology, population genetics, mathematics, statistics and computer science. Biologists who have used phylogenetic software programs to analyze their own data will find the book particularly rewarding, although it should appeal to anyone seeking an authoritative overview of this exciting area of computational biology.

What sets this books apart is the authority and thoughtfulness with which it is written, the thorough coverage of the relevant literature, and the great care that has been taken in the computational examples to compare different methods on the same set of data, and to present the results clearly. It will be an invaluable resource both for new graduate students and established researchers. It will be a major source for insight and enormously helpful for anyone who wants to understand molecular phylogenies. The Quarterly Review of Biology


PREFACE; 1. Models of Nucleotide Substitution; 2. Models of Amino Acid and Codon Substitution; 3. Phylogeny Reconstruction: Overview; 4. Maximum Likelihood Methods; 5. Bayesian Methods; 6. Comparison of Methods and Tests on Trees; 7. Molecular Clock and Estimation of Species Divergence Times; 8. Neutral and Adaptive Protein Evolution; 9. Simulating Molecular Evolution; 10. Perspectives; APPENDIXES; REFERENCE

Write a review

There are currently no reviews for this product. Be the first to review this product!

Bestsellers in this subject

Statistics for Ecologists Using R and Excel

NHBS Price: £34.99 $49/€40 approx

Choosing and Using Statistics

NHBS Price: £28.50 $40/€32 approx

Community Ecology

NHBS Special Offer Price: £23.99 £39.99 (Save £16.00) $34/€27 approx (ends 31/03/2018)

Handbook of Meta-analysis in Ecology and Evolution

NHBS Special Offer Price: £39.95 £65.95 (Save £26.00) $56/€46 approx (ends 31/03/2018)

Statistics for Terrified Biologists

NHBS Price: £26.50 $37/€30 approx

VAT: GB 407 4846 44
NHBS Ltd is registered in England and Wales: 1875194