Atomic Evidence takes an evidence-based approach to current knowledge about biomolecules and their place in our lives, inviting readers to explore how we know what we know, and how current gaps in knowledge may influence the way we approach the information. Biomolecular science is increasingly important in our everyday life, influencing the choices we make about our diet, our health, and our wellness. Often, however, information about biomolecular science is presented as a list of immutable facts, discouraging critical thought. Atomic Evidence will introduce the basic tools of structural biology, supply real-life examples, and encourage critical thought about aspects of biology that are still not fully understood.
Chapter 1. The Protein Data Bank
Chapter 2. Seeing is Believing: Methods of Structure Solution
Chapter 3. Visualizing the Invisible World of Molecules
Chapter 4. The Twists and Turns of DNA
Chapter 5. The Central Dogma
Chapter 6. The Secret of Life: The Genetic Code
Chapter 7. Evolution in Action
Chapter 8. How Evolution Shapes Proteins
Chapter 9. The Universe of Protein Folds
Chapter 10. Order and Chaos in Protein Structure
Chapter 11. Molecular Electronics
Chapter 12. Green Energy
Chapter 13. Peak Performance
Chapter 14. Cellular Signaling Networks
Chapter 15. GPCRs Revealed
Chapter 16. Signaling with Hormones
Chapter 17: Single Molecule Chemistry: Enzyme Action and the Transition State
Chapter 18. Seven Wonders of the World of Enzymes
Chapter 19. Building Bodies
Chapter 20. Coloring the Biological World
Chapter 21. Amazing Antibodies
Chapter 22. Attack and Defense: Weapons of the Immune System
Chapter 23. Reconstructing HIV
David Goodsell is an Associate Professor of Molecular Biology at the Scripps Research Institute, where he currently divides his time between research and science outreach. His research centers on methods for predicting and analyzing biomolecular complexes, and application of these methods to drug discovery and drug design. His science outreach work builds on his work in molecular graphics and computation. He currently authors a monthly column at the RCSB Protein Data Bank that presents molecular structure and function for general audiences. He has also written three general-interest books including The Machinery of Life and Our Molecular Nature. He has also collaborated with science museums, filmmakers and popular authors on the creation of educational and outreach materials.