Hans Krebs, Volume 1 The Formation of a Scientific Life 1900-1933

About this book

This is the first volume of the definitive biography of Hans Krebs, one of the world's foremost biochemists. It begins with the early work of Krebs in Germany, where, working with Otto Warburg, he discovered the urea cycle in 1932. This early achievement, coupled with the discovery of the citric acid cycle, are viewed as the foundations upon which the modern structure of intermediary metabolism is built. During the writing of this fascinating history, the author not only had access to a complete set of Krebs' key laboratory notebooks, but to the man himself through five years of insightful interviews. Holmes captures Krebs' activities at a level of intimacy that reveals scientific creativity at work. The story weaves together the investigative pathway with the professional and personal life of the investigator. The Krebs biography is certain to fascinate biochemists and historians of science alike.

Contents

- Intermediary metabolism in the first third of the twentieth century
- Boyhood in Hildesheim
- Outward movement
- Clinical years
- The research apprentice
- Initiative and dependence
- Moves toward autonomy
- Freiburg: The foundation of a career
- The ornithine effect
- The formation of urea
- The rewards of success
- The brief life of a Freiburg school of metabolism
- Reflections on the formation of a scientific life

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