Phenomics

About this book

As our ability to acquire massive amounts of information about genome variation accelerates it is becoming increasingly clear that to make maximum use of this information we also need well-structured, systematic data on the phenotypic consequences of genomic changes. Phenomics is the new discipline of using standardized measurement techniques to characterize the phenotypic effects of random or systematic genome modifications (for example randomly generated mutations or systematic gene knockouts). This approach is now being used in an increasing range of species and systems. In Phenomics, experts working in phenomics in most of the major species and systems that are currently being studied present overviews of the field from their different, but overlapping perspectives.

Contents

Introduction to phenomics
John M. Hancock
Overview of phenomics/human phenomics
Peter N. Robinson (Charité, Berlin)
Mouse phenomics and the International Mouse Phenome Consortium
John M. Hancock & Michael Dobbie (University of Cambridge, UK and Australian Phenotype Network, Canberra, Australia)
Zebrafish phenomics
Elisabeth Bush-Nentwich (Wellcome Trust Sanger Institute, UK)
Systematic cell phenotyping
Jean-Karim Heriché (EMBL Heidelberg, Germany)
Systematic phenotyping of Arabidopsis
Christine Granier (Laboratoire d'Ecophysiologie des Plantes sous Stress Environnementaux (LEPSE), INRA-AGRO-M, Montpellier, France)
Phenomics of crop plants
John Doonan (Aberystwyth University, UK)
Systematic phenotyping in yeast
Anders Blomberg (University of Gothenburg, Sweden)
Systematic phenotyping of bacteria
Carol Gross (University of California at San Francisco, USA)
Overview of phenotype databases
Philip Groth, Bertram Weiss (Bayer Pharma AG, Berlin, Germany)
Phenotype informatics and ontologies
John M. Hancock & Georgios Gkoutos (University of Cambridge, UK and Aberystwyth University, UK)

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