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Dictyostelium: Evolution, Cell Biology, and the Development of Multicellularity

Series: Developmental and Cell Biology Series Volume: 38

By: Richard H Kessin

Cambridge University Press

Paperback | Aug 2010 | #187730 | ISBN-13: 9780521152822
Availability: Usually dispatched within 6 days Details
NHBS Price: £36.99 $49/€42 approx

About this book

Dictyostelia are soil amoebae capable of extraordinary feats of survival, motility, chemotaxis, and development. Characterised by their ability to transform from a single-celled organism into an elaborate assemblage of thousands of synchronously-moving cells, Dictyostelids are often referred to as 'social amoebae', and have been the subjects of serious study since the 1930s. Research in this area has been instrumental in understanding many problems in cellular biology. Beginning with the history of Dictyostelids and discussing each stage of their development, this book considers the evolution of this unique organism, analyses the special properties of the Dictyostelid genome, and presents in detail the methods available, at the time of the book's original publication in 2001, to manipulate their genes.

Review of the hardback: '... a beautiful balance between the well understood and the relatively unexplored ... it offers so much in such a tiny volume. I thoroughly recommend it.' P. R. Fisher, Soil Biology and Biochemistry Review of the hardback: '... a major achievement and will serve the field well for several years to come.' Jeffrey Williams, Trends in Genetics Review of the hardback: '... an excellent and up-to-date summary of how social amoebae do it, and is bristling with fascinating biological answers and questions.' John A. Lee, Geologist Review of the hardback: 'This book is an excellent and up-to-date summary of how social amoebae do it, and is bristling with fascinating biological answers and questions.' Biologist Review of the hardback: '... well organized and superbly presented ... easy to read and very accessible to the newcomer to the field ... the time is certainly right for a book to introduce this organism and its research to a wider audience. This is the ideal book.' Peter A. Thomason, Nature Cell Biology Review of the hardback: 'This will be the key reference work on this fascinating genus for decades, and a 'must' not only for developmental biologists but also the many mycologists who continue to dabble in and be fascinated by slime moulds.' Mycol. Research


Preface; 1. A brief introduction to Dictyostelium discoideum and its relatives; 2. A history of research on Dictyostelium discoideum; 3. The evolutionary biology of Dictyostelium; 4. The genome and genetics; 5. Membranes and organelles of Dictyostelium; 6. Cell motility and the cytoskeleton; 7. The transition from growth to development: from starvation to self sustaining cAMP signal relay; 8. Chemotaxis and aggregation; 9. Differentiation and adhesion in the aggregate; 10. Behavior of cells in the slug; 11. Culmination; 12. Formation and germination of spores; 13. Resources; References; Index.

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