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Systems biology is an approach to combine molecular data, genetic evolution, environmental cues and species-interaction with the understanding, modeling and prediction of active biochemical networks. Green Systems Biology provides a thorough introduction to the field and treats applications of systems biology in ecology, nutrition, biofuel and drug discovery. With increasing problems in feeding the world population, changes in the global climate and limited energy resources from fossil fuels, researchers and industry are turning to plants as a resource of raw materials for solving the human dilemma on earth. At the brink of the third „Green Revolution", systems biology is identifying key issues for the investigation of plant model systems up to whole ecosystems.