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The purpose of this Manual of Diagnostic Tests for Aquatic Animals (Aquatic Manual) is to provide a uniform approach to the detection of the diseases listed in the OIE Aquatic Animal Health Code, together with additional diseases so that the requirements for the control of animal diseases and health certification in connection with trade in aquatic animals and aquatic animal products can be met. Although many publications exist on the detection and control of aquatic animal diseases, the Aquatic Manual is a key and unique document describing the methods that can be applied to the OIE-listed diseases in aquatic animal health laboratories all over the world, thus increasing efficiency and promoting improvements in aquatic animal health world-wide. The requirements published in the Aquatic Manual are recognised as international standards by the World Trade Organization.