By: JR Hanson
153 pages, Figs, tabs
Natural products are compounds that are produced by living systems and the secondary metabolites are those which give particular species their characteristic features. These natural products include polyketides, terpenoids, phenylpropanoids, alkaloids and antibiotics. The study of these natural products has played a major part in the development of organic and medicinal chemistry and we are now starting to understand the important ecological role that these compounds have. The aim of this publication is to describe the major features of these compounds and the way in which chemical and physical methods have been used to establish their structures and then to show how these structures can be rationalized in biosynthetic terms. The first chapter describes the classes of natural product, their biological activity and isolation. Subsequent chapters attempt to link chemical and spectroscopic strategies in structure elucidation, contrasting the classical chemical strategies that were used in the past with modern spectroscopic methods. The final chapter describes the biosynthesis of natural products. The elucidation of the structures of natural products brings together many elements taught in courses on functional group chemistry, stereochemistry and elementary spectroscopy. This book should therefore be welcomed by lecturers and students of second-year chemistry courses.
... This tutorial text is highly recommended for all chemists. -- Chemistry in Australia, April 2004, p 30 Chemistry in Australia A useful introduction to natural products and will make a good undergraduate tutorial text. -- Education in Chemistry, November 2004 issue (John Mann) Education in Chemistry
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