Polymer and Cell Dynamics Multiscale Modelling and Numerical Simulations

About this book

Polymer and cell dynamics play an important role in processes like tumor growth, metastasis, embryogenesis, immune reactions and regeneration. Polymer and Cell Dynamics – based on an international workshop on numerical simulations of polymer and cell dynamics in Bad Honnef (Germany) in 2000 – provides an overview of the relevant mathematical and numerical methods, their applications and limits. The contributions are from the fields of applied and numerical mathematics, scientific computing, theoretical physics, molecular biophysics, cell and molecular biology as well as chemical and biomedical engineering. Polymer and Cell Dynamics will be of interest to scientists and advanced undergraduates in the fields of biotechnology, biomedicine, applied mathematics, biomathematics, biophysics and bioinformatics.

Contents

Introduction

Part I: Molecular Dynamics and Protein Configuration
- Introduction to Part I
- Molecular Dynamics Studies of Micelle and Capsid Self-assembly
- A Functional Study on Saposin B and C Using Experimentally Validated Models
- The Morph Server and the Macromolecular Motions Database: A Standardized System for Analyzing and Visualizing Macromolecular Motions in a Database Framework

Part II: Polymer Dynamics and Cell Motility
- Introduction to Part II
- Brownian Dynamics of Flexible Polymers in Flow
- A Microscopic Model for the Dynamics of Actin Filaments in Motility Assays and Its Numerical Simulation
- Multiparticle Modeling of Actin-Myosin Networks: From Molecular Interactions to Cell Motility
- Analysis of Cell Motility Combining Cytomechanical Model Simulations and an Optical Flow Method
- Micropipet Aspiration of the Human Neutrophil
- Physical-Object-Oriented 3D Simulations of Cell Deformations and Migration

Part III: Multicellular Dynamics
- Introduction to Part III

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