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Rice has been chosen as a model cereal for functional genomics because of its well understood genetics. In addition, there is great similarities among all the cereals and grasses: any understanding of rice genes is directly applicable to the genes of other cereals. This book details rice functional genomics. It takes a multi-pronged genome-wide approach using structural similarities, expression profiles, and mutant phenotypes. Coverage includes the current status of genome sequencing and annotation, various tools, and resources being developed worldwide.
Introduction.- Rice genome sequence.- Gene annotations: the beginning of functional genomics.- Genome-wide RNA expression profiling.- Genome-wide Protein expression profiling.- Naturally occurring alleles.- Induced mutants and TILLING.- T-DNA Insertional mutants.- Transposon Insertional mutants.- Retrotransposon Insertional mutants.- Gene targeting by homologous recombination.- Gene silencing.- Activation tagging.- Bioinformatics. Comparative Genomics.
From the reviews: "This book represents an excellent set of (reviewed) reviews that explains what is happening in the world of rice genomic research now. ! This is a useful book for genetic resources workers because understanding the way in which the genome works is generating huge numbers of mutants required for forward (from phenotype to genome sequence) and reverse genetics (genome sequence to phenotype)." (D. Vaughan, Genetic Resources and Crop Evolution, Vol. 54, 2007)