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It features several new sections and chapters on areas such as sequence-based analysis, biochip data analysis, and generalised bioinformatics. The author also provides the latest lists of statistical and linkage analysis software and their Web links, as well as SAS codes to offer assistance with difficult problems.
Introduction. Biology in Genomics. Introduction to Genomics. Statistics in Genomics. Bioinformatics. Resampling and Simulation in Genomics. Parameter Space and Genomics Hypothesis. Single-Locus Models. Two-Locus Models: Controlled Cross. Two-Locus Model: Natural Population. Two-Locus Model: Using Disequilibrium. Linkage Grouping and Locus Ordering. Multi-Locus Model. Linkage Map Merging. QTL Mapping: Introduction. QTL Mapping: Single-Marker Analysis. QTL Mapping: Interval Mapping. QTL Mapping: Natural Population. QTL Mapping: Statistical Power. QTL Mapping: Future Consideration. Methods for High Throughput Experiments. Computer Resources. Sequence Analysis. Function Prediction Based on Sequence. Structure Prediction. Introduction to High Throughput Experiments. Introduction to Biochip Design. Information Management. Biochip Data Analysis. Glossary. Bibliography. Author Index. Subject Index.
Bio-Informatics Group, North Carolina, USA Chip Screen BioSciences Ltd., Guangdong, China