The study of stem cell research has recently gained the attention from a growing, multidisciplinary community of scientists; this exponential growth of interest is driven by the hope of discovering cures for several diseases through transplantation medicine.
This title serves this developing community as it reveals new aspects of stem cell research by specifically covering studies focused on spermatogonial stem cells, uniparental embryonic stem cell lines, the generation of gametes from stem cells, reprogramming germ cells to stem cells, nuclear and somatic cell genetic reprogramming, tissue engineering and mechanotransduction of stem cells and finally the development of stem cell technologies for the treatment of deafness, heart disease, corneal injury and diabetes.
Chapters: Human Embryonic Stem Cells: Their nature, properties and uses Bongso A, Fong CY. Production of Uniparental Embryonic Stem Cell Lines Eckardt S, McLaughlin KJ. Parthenogenetic embryonic stem cells in non-human primates Ragina NP, Cibelli JB. Nuclear and somatic cell genetic reprogramming Zuccotti M, Garagna S, Redi CA. Reprogramming male germ cells to pluripotent stem cells Mardanpour P, Guan K, Glaeser T, Lee JH, Nolte J, Wulf G, Hasenfuss G, Engel W, Brustle O, Nayernia K. Pluripotent stem cell epigenetics during development and cancer Noelia Andollo N, Boyano M. D, Zalduendo MDM, Arechaga J. Observing and manipulating pluripotency in normal and cloned mouse embryos Balbach ST, Cavaleri FM, Gentile L, Arauzo-Bravo MJ, Scholer HR, Crosetto N, Boiani M. Current developments in genetically manipulated mice Matthaei KI. Differentiating gametes from stem cells Marques-Mari AI, Medrano JV, Simon C. Spermatogonial stem cells Rooij DG. Regulated transcripts and co-regulated microRNAs in male spermatogonial stem cells Olive V, Cuzin F, Rassoulzadegan M. Human Mesenchymal Stem cells: Basic biology and clinical applications for bone tissue regeneration Abadia BM, Saeed H, Kassem M. Clinical cell therapy for heart disease Stamm C, Nasseri B, Hetzer R. Embryonic stem cells, cardiomyoplasty and the risk of teratoma formation A aric T, Frenzel LP, Fatima A, Gupta MK, Hescheler J. Neural differentiation of human embryonic stem cells and their potential application in a therapy for sensorineural hearing loss Trachoo O, Rivolta MN. Stem cell transplantation supports the repair of injured olfactory neuroepithelium after permanent lesion Franceschini V, Bettini S, Riccardo Saccardi R, Revoltella RP. Strategies towards beta-cell replacement Roche E, Vicente-Salar N, Arribas M, Paredes B. Corneal epithelial stem cells and their therapeutic application Kolli S, Lako M, Figueiredo F, Ahmad S. Tissue engineered scaffolds for stem cells and regenerative medicine Hossein Hosseinkhani, Mohsen Hosseinkhani. Mechanotransduction and its Role in Stem Cell Biology Wolf CB, Mofrad MRK.