Ecotoxicity and Human Health A Biological Approach to Environmental Remediation

About this book

The particular focus of this work is the extent and nature of hazardous waste sites and how their effects may be studied in humans and other systems, using in vitro models, biomarkers of cellular and molecular damage and animal models.

Contents

Introduction, F.J. de Serres and A.D. BloomHazardous Waste: Nature, Extent, Effects, and Societal Responses, B.L. JohnsonIntroductionNature and Extent of Waste GenerationEffects of Hazardous Waste on Human HealthEffects of Hazardous Waste on EcosystemsSocietal Response: Laws and International ConventionsRemediation of Hazardous WastesSocietal Response: Environmental EthicsSummary and ConclusionsAcknowledgmentsReferencesEcotoxicology: Environmental Fate and Ecosystem Impact, C.E. WeinsteinThe Relationship Between Human and Ecological HealthBiological Interactions with Environmental ContaminantsModelingEcotoxicology and BiotaEcosystem Effects of Persistent ToxicantsConsiderations for BioremediationReferencesIntegration of Complex Mixture Toxicity and Microbiological Analyses for Environmental Remediation Research, L.D. Claxton, V.S. Houk, and S.E. GeorgeUnderstanding the ProblemsEffect of the Dynamic Complexity of Hazardous Waste Sites Upon Understanding Potential Toxic ExposuresResearch Strategies for MicroorganismsImpact of Integrated Biological Analyses Upon Exposure and Risk Assessment MethodsSummary and ConclusionsAcknowledgmentsReferencesBiomarkers of DNA Damage, L.R. ShugartBiomarkers: An OverviewDNA Damage as a BiomarkerStrategies for Biomarker UseStrategies for Biomarker EvaluationIn Situ StudiesSummaryAcknowledgmentsReferencesIn Situ Evaluation of Genetic Hazards of Complex Chemical Mixtures, S.S. Sandhu, W.R. Lower, and Y.R. AhujaIntroductionDetection of Genetic Hazards at Industrial Waste SitesGenotoxicity Assessment in Aquatic EnvironmentsIntegration, Interpretation, and Limitation of DataAcknowledgementsReferencesWildlife Toxicity in Biomonitoring and Bioremediation: Implications for Human Health, K. McBee and R.L. LochmillerIntroductionPopulation DynamicsMixed Function Oxidase (MFO) Enzyme SystemImmunotoxicityGenotoxicityExtrapolation from Wildlife Models to Potential Human EffectReferencesEnvironmental Bioremediation: Approaches and Processes, C. Bonaventura, J. Bonaventura, and D.F. BodishbaughBioremediation DefinedBioremediation as a Natural ProcessEnvironmental Health and Human Health Aspects of Environmental ContaminationGeneral Steps and Methods in BioremediationAssessment of Bioremediation and BiodegradationSummary and ConclusionsReferencesEnvironmental Bioremediation: Applications and New Horizons, C. Bonaventura, J. Bonaventura, and D.F. BodishbaughPractical BioremediationBioremediation Technologies in PracticeFuture Prospects for Environmental BioremediationResearch Needed to Advance Bioremediation TechnologiesSummary and ConclusionsReferencesQuantitative Modeling and Analysis in Environmental Studies, D.P. GaverIntroductionModeling Groundwater: A Specific System Relevant to Remediation IssuesCompartment and Pharmacokinetic ModelsHuman Exposure Modeling and AnalysisDose-Response Mod

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