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Explores the origin, maintenance and significance of genetic variation, with each of the four chapters focusing on the basic elements of population genetics and their application to real-life situations. Aimed at students, it includes problems for solution using authentic data, with fully worked-out solutions.
Part 1 Genetic variation: genetic and molecular essentials; types of polymorphisms; organization of genetic variation; inbreeding. Part 2 The causes of evolution: mutation; migration; natural selection; random genetic drift. Part 3 Molecular population genetics: molecular polymorphisms; patterns of change in nucleotide and amino acid sequences; polymorphism and divergence; molecular phylogenetics; transposable elements. Part 4 The genetic architecture of complex traits: types of complex traits; phenotypic variation; genetics and environment; artificial selection; correlation between relatives; quantitative genetics of natural populations; complex traits with discrete expression; quantitative trait loci (QTLs).