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The bacterium, Bacillus thuringiensis (B.t), is used worldwide as an effective biological control agent for many species of insect pest, either by crop spraying or genetic engineering of crop plants. It is a topical subject of interest to a wide range of disciplines as questions have recently been raised due to health concerns over inhalation of the bacterial spores, and fears of gene-swapping. This text provides a definitive source of information on the environmental, non-target and human safety of these products.