Chromosome Biology

About this book

Cytogenetics has undergone a revolution as a result of the phenomenal advances in molecular genetics and techniques. Students of genetics, crop science and plant breeding, entomology, animal science, and related fields will benefit from this comprehensive and practical textbook.

Contents

Chromosomes studies from a historical perspective. Microscopes: basic tools for studying chromosomes. Chromosomes in the mitotic cell cycle. The organization of DNA sequences in protosomes and chromosomes. The variable structure and folding of DNA. The synthesis of DNA and histones. Meiosis: an alternative view of chromosomes. Chromosome morphology and number. Exploring chromosomes by in situ biochemical reactions. Molecular analysis of classical cytogenetic landmarks. Structural stability of chromosomes. Losses or gains of chromosome segments. Rearrangements of chromosome numbers. Deviations rom multiples of basic chromosome numbers. Origin and analysis of haploids. Locating genes in diploids using chromosome aberrations. Locating genes in polyploids using chromosome aberrations. The genetic and molecular mapping of chromosomes. Uses and significance of chromosome changes. Gene transfers by chromosome manipulations. Engineering the genome. Cytoplasmic DNA and maternally inherited traits. Important experimental organisms.

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